ALLERGY, RESPIRATORY
Traffic, Dust Linked to Asthma in Kids
New Spray Could Benefit Cystic Fibrosis Patients
Using Music and Sports to Improve Kids' Asthma
ALTERNATIVE MEDICINE
Many Cancer Patients Turn to Complementary Medicine
Regular Yoga May Improve Eating Habits
Acupuncture May Trigger Natural Painkiller
ANIMAL CARE
Safe Toys for Dogs
Separation Anxiety, Canine-Style
Beware of Dog Bites
BONES & JOINTS
Soccer's a Winner for Building Bone Health in Girls
Bone Density Predicts Chances of Breast Cancer
Vitamin K Doesn't Slow Bone Loss
CANCER
Study Suggests Link Between Cell Phones and Brain Tumors
Smoking Exposure Now Linked to Colon, Breast Cancers
Red Meat No No No But Oily Fish Yes Yes Yes
CAREGIVING
Most Women Struggle With Rising Health Care Costs
Omega-3 Fatty Acid May Help 'Preemie' Girls' Brains
With Age Comes Greater Risk of Hypothermia
CIRCULATORY SYSTEM
Obesity Linked to Heart Failure Risk
Review Confirms Links Between Diet, Heart Health
Migraines in Pregnancy Boost Vascular Risks
COSMETIC
What to Do If You Have Unsightly Veins
With Psoriasis, the Internet May Offer Hope
New Genetic Links to Baldness Discovered
DENTAL, ORAL
A Sweet Way to Shield Baby's Teeth
Holistic Dentistry-My View
An Oral Approach to Heart Disease
DIABETES
Treatment for Type 2 Diabetes Updated
Whole Grains Take a Bite Out of Type 2 Diabetes Risk
Vitamin K Slows Insulin Resistance in Older Men
DIET, NUTRITION
Eating Vegan or Raw-Vegan at Regular Restaurants
Fruits, Vegetables, Teas May Cut Smokers' Cancer Risk
Vitamin D May Help Keep Aging at Bay
DISABILITIES
Review Finds Marijuana May Help MS Patients
Could Your Cell Phone Help Shield You From Alzheimer's?
ENVIRONMENTAL HEALTH
Global Warming May Bring More Respiratory Woes
Clear Skies Have Become Less So Over Time, Data Show
Radiation Exposure Linked to Aggressive Thyroid Cancers
EYE CARE, VISION
Cases of Age-Related Farsightedness to Soar
Don't Lose Sight of Halloween Safety
Eye Problems, Hearing Loss May Be Linked
FITNESS
Be Healthy, Spend Less
Run for Your Life
After a Stroke, Light Exercise Gets Hands, Arms Working Again
GASTROINTESTINAL PROBLEMS
Japanese Herbals May Ease Gastro Woes
Olive Oil May Protect Against Bowel Disease
Peppermint Oil, Fiber Can Fight Irritable Bowel
GENERAL HEALTH
Time to Remind Teens About Sun Protection
Eating More Soy May Be Good For Your Lung Function
Eating Healthy : You Can Live Longer
HEAD & NECK
Ski Helmets Encouraged for All
Zen May Thicken Brain, Thwart Pain
Many Children Will Outgrow Headaches
HEALTH & TECHNOLOGY
Subway Defibrillators Save Lives
Airport Full Body Scanners Pose No Health Threat: Experts
E-Mailing Your Way to Healthier Habits
HEARING
Noise Hurts Men's Hearing More, Study Shows
Summer Sounds Can Lead to Hearing Loss
HEART & CARDIOVASCULAR
Vigorous Exercise Cuts Stroke Risk for Men, Not Women
Fewer Heart Attacks After England Goes Smoke-Free
Ginkgo Won't Prevent Heart Attack, Stroke in Elderly
INFECTIOUS DISEASE
Swine Flu Now Reported in All 50 States
Older Adults May Have Some Immunity to Swine Flu
Chinese 'Devil Dung' Plant Could Be a Swine Flu Fighter
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
Folic Acid Reduces Infant Heart Defects
Teen Internet Addicts More Likely to Self-Harm: Study
Meaningful Conversations Boost Kids' Language Skills
MEN'S HEALTH
Low Vitamin D Levels May Boost Men's Heart Attack Risk
Eating Fast Until Full Triples Overweight Risk
Physical Activity May Prolong Survival After Colon Cancer
MENTAL HEALTH
Consciousness Helps the Mind and Body Work Together
Music Soothes Anxiety as Well as Massage Does
Drink Away Dementia?
PHYSICAL THERAPY
PREGNANCY
Breast-Feeding Benefits Moms and Babies
Calcium Supplements Cut Blood Lead Levels During Pregnancy
Pregnant Women Exposed To Certain Pollutants Could Lower Childs IQ
SENIORS
Vitamin D May Help Keep Aging at Bay
Older People at Greater Risk of Swine Flu Death
Memory Loss Help from Brain Supplement Prevagen
SEXUAL HEALTH
SLEEP DISORDERS
Moderate Aerobics May Ease Insomnia Symptoms
Better Sleep, Grades Seem to Go Up
6 to 8 Hours of Shut-Eye Is Optimal for Health
WOMEN'S HEALTH
Natural Therapies for Menopause
Being Active an Hour a Day Puts Brakes on Weight Gain
Supplements Might Reduce Breast Cancer Risk
Add your Article

Antioxidants Blunt Exercise Benefit, Study Shows

By Steven Reinberg
HealthDay Reporter

MONDAY, May 11 (HealthDay News) -- Exercise helps increase insulin sensitivity and ward off diabetes, but taking supplemental antioxidants such as vitamins C and E actually blunts that benefit, researchers report.

Exercise helps increase the body's sensitivity to insulin by making reactive oxygen species, or "free radicals," which antioxidants work against. These free radicals are thought to damage cells and speed the aging process, but they are also used by the body to prevent cell damage after exercising, the researchers say.

"When you exercise you do improve your insulin sensitivity, and if you are at risk for diabetes improving insulin sensitivity is good," said researcher Dr. C. Ronald Kahn, the Mary K. Iacocca Professor at the Joslin Diabetes Center and Harvard Medical School.

Part of the reason that exercise improves insulin sensitivity is that it causes oxidative stress on the muscles. The muscles respond to this stress by creating free radicals, Kahn said.

"If you take antioxidants like vitamins C and E, you block the oxidative stress response, but you also block the beneficial effects of exercise on insulin sensitivity," he said.

The report is published in this week's online edition of the Proceedings of the National Academy of Sciences.

For the study, Kahn's team looked at the benefit of exercise in increasing insulin resistance in 39 young men, roughly half of whom were taking supplemental vitamins C and E.

Kahn's group found that men taking vitamin supplements had no change in their insulin resistance, but men not taking vitamins had an increase in free radicals, which increases insulin resistance. A month after stopping the vitamin supplements insulin sensitivity was restored, the researchers noted.

"If you are exercising, in part, to reduce diabetes risk, you shouldn't take vitamin C and E, because you are going to block some of the beneficial effect of the exercise to prevent the diabetes," Kahn said.

Dr. David L. Katz, director of the Prevention Research Center at Yale University School of Medicine, thinks this study raises doubts about the benefits of taking antioxidant supplements, but not about the value of these vitamins in the foods people eat.

"We have long held out hope that antioxidant supplements, among them vitamin C, vitamin E, beta carotene, and more recently lycopene and others, would help prevent diseases from the common cold to cancer, heart disease to diabetes," Katz said. "But to date, virtually all of the best research evidence is contrary to this hope."

This study has a counter-intuitive conclusion, namely that antioxidant supplements may actually interfere with the beneficial effects of exercise on insulin sensitivity, Katz said.

"This is a small and short-term study, and thus cannot tell us definitively that antioxidant supplements are harmful in diabetes or the insulin-resistant state that often precedes it. But that is precisely what the study suggests may be true," Katz said.

For now, there is substantial uncertainty about any health benefits and the potential harms of antioxidants as supplements, Katz said. "But we have no such confusion about the powerful health-promoting effects of wholesome, mostly plant-based diets and regular physical activity."

More information

For more information on antioxidants, visit the U.S. National Library of Medicine.



SOURCES: C. Ronald Kahn, M.D., Mary K. Iacocca Professor, Joslin Diabetes Center and Harvard Medical School, Boston; David L. Katz, M.D., M.P.H., director, Prevention Research Center, Yale University School of Medicine, New Haven, Conn.; May 11-15, 2009, Proceedings of the National Academy of Sciences, online

Last Updated: May 11, 2009

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