ALLERGY, RESPIRATORY
Keep Asthma, Allergies at Bay for the Holidays
Folic Acid Might Offer Allergy Relief
Childhood Food Allergies on the Rise
ALTERNATIVE MEDICINE
Music Therapy For Prehistoric Man?
Eight Spiritual Universal Principles in the Art of Practice
Acupuncture Eases Breast Cancer Treatment Side Effects
ANIMAL CARE
Separation Anxiety, Canine-Style
Safe Toys for Dogs
Beware of Dog Bites
BONES & JOINTS
Active Young Women Need Calcium, Vitamin D
Weight Loss Might Not Curb Knee Arthritis
Study Examines How Rheumatoid Arthritis Destroys Bone
CANCER
Many Ignore Symptoms of Bladder Trouble
Lifting Weights Can Ease Arm Swelling in Breast Cancer Survivors
Tanning Beds Shown To Raise Cancer Risk, Study Says
CAREGIVING
Children's Bath Products Contain Contaminants
Study Links Pesticides to Birth Defects
Tiniest Babies Carry Biggest Costs
CIRCULATORY SYSTEM
Support Network May Play Role in Benefits of Drinking
Review Confirms Links Between Diet, Heart Health
Varicose Veins May Mask Larger Problem
COSMETIC
What to Do If You Have Unsightly Veins
Gum Chewing May Cut Craving for Snacks
With Psoriasis, the Internet May Offer Hope
DENTAL, ORAL
Hormones May Be to Blame for Women's Cavity Rates
Mom's Vitamin D Levels Affect Baby's Dental Health
An Oral Approach to Heart Disease
DIABETES
Treatment for Type 2 Diabetes Updated
Fructose-Sweetened Drinks Up Metabolic Syndrome Risk
Arthritis Hits More Than Half of Diabetics
DIET, NUTRITION
Western Diet Linked To Heart Disease, Metabolic Syndrome
Want to Stop Cancer? You Can, Experts Say
Low Vitamin A, C Intake Tied to Asthma Risk
DISABILITIES
Review Finds Marijuana May Help MS Patients
Could Your Cell Phone Help Shield You From Alzheimer's?
ENVIRONMENTAL HEALTH
Walkable Neighborhoods Keep the Pounds Off
Years of Exposure to Traffic Pollution Raises Blood Pressure
Meat-Eating Dinosaurs Used Legs and Arms Like Birds
EYE CARE, VISION
Eye Problems, Hearing Loss May Be Linked
Certain Diabetes Drugs May Pose Eye Risk
Ordinary Chores Cause Half of All Eye Injuries
FITNESS
Living With Less TV, More Sweat Boosts Weight Loss
More Steps a Day Lead to Better Health
Tai Chi: An Ideal Exercise for Many People with Diabetes
GASTROINTESTINAL PROBLEMS
Soothing Imagery May Help Rid Some Kids of Stomach Pain
Japanese Herbals May Ease Gastro Woes
Bowel Prep Harder on Women Than Men
GENERAL HEALTH
Life Expectancy in U.S. Hits New High
Laugh and the World Understands
Music Therapy For Prehistoric Man?
HEAD & NECK
Zen May Thicken Brain, Thwart Pain
Many Children Will Outgrow Headaches
Ski Helmets Encouraged for All
HEALTH & TECHNOLOGY
E-Mailing Your Way to Healthier Habits
Save Your Aging Brain, Try Surfing The Web
Using Light Therapy to Silence Harmful Brain Activity
HEARING
Noise Hurts Men's Hearing More, Study Shows
Summer Sounds Can Lead to Hearing Loss
HEART & CARDIOVASCULAR
Risk Factor for Stroke More Common Among Whites
Estrogen May Help Men's Hearts
Relaxation Tapes or Mozart Lower Blood Pressure
INFECTIOUS DISEASE
Hand Washing 10 Times a Day May Help Keep Flu Away
Swine Flu Now Reported in All 50 States
Viral Infection Might Trigger High Blood Pressure
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
Older People at Greater Risk of Swine Flu Death
Bullying Seems to Affect Kids Years Later
Plastics Chemical Tied to Aggression in Young Girls
MEN'S HEALTH
Whole Grains, Bran May Fight Hypertension in Men
Soy Linked to Low Sperm Count
Low Vitamin D Levels May Boost Men's Heart Attack Risk
MENTAL HEALTH
Eight Spiritual Universal Principles in the Art of Practice
Musicians' Brains Tuned to Emotions in Sound
Vitamin C Protects Some Elderly Men From Bone Loss
PAIN
Acupuncture, Real or Fake, Eases Back Pain
Are We Exercising Pain Away? Not So Much.
'Cell Phone Elbow' -- A New Ill for the Wired Age
PHYSICAL THERAPY
PREGNANCY
Woman in America Are Delaying Motherhood, Study Says
Pre-Pregnancy Weight Linked to Babies' Heart Problems
Pregnant Women Exposed To Certain Pollutants Could Lower Childs IQ
SENIORS
Older Adults May Have Some Immunity to Swine Flu
Life Expectancy in U.S. Hits New High
Exercise Helps Reduce Falls in Young and Old
SEXUAL HEALTH
SLEEP DISORDERS
Sleeping Could Help Women Lose The Baby Fat
6 to 8 Hours of Shut-Eye Is Optimal for Health
Daylight Savings: Not a Bright Time for All
WOMEN'S HEALTH
Mom and Baby Alike May Benefit From Exercise
Supplements Might Reduce Breast Cancer Risk
Whole Grains, Bran May Fight Hypertension in Men
Add your Article

Birthmark or Blood Vessel Problem?

THURSDAY, Jan. 29 (HealthDay News) -- Genetics may help doctors tell sooner whether common birthmarks will become serious vascular malformations, a new study says.

"Our findings may lead to earlier diagnosis, precise classification and, ultimately, targeted therapy for infants with hidden congenital vascular malformations," study author Ramani Ramchandran, associate professor of pediatrics in the division of developmental biology at Medical College of Wisconsin, said in a news release issued by the school.

In two studies published in the Jan. 29 issue of Blood, researchers found that two genes -- Dusp-5 and Snrk-1 -- play a role in blood vessel formation.

"We believe that specific mutations in Dusp-5 and Snrk-1 may provide keys to distinguish between hemangiomas [birthmarks] and vascular malformations," Ramchandran said. "Vascular malformations fall into different classes based on the affected vessel type. For example, venous malformations affect veins, and arterial malformations affect arteries. Mutations in Snrk-1 may actually help classify vascular malformations as venous or lymphatic malformations and thus distinguish them from other malformations."

The studies were done in zebra fish embryos, and the team then identified similar mutations in human tissue, according to the release. The pathway these genes follow in people has not been discovered, according to Ramchandran, who indicated that such a finding could be the breakthrough needed to identify causes of vascular malformation.

Future research will try to quantify what role the mutations have on predicting the condition as well as its severity, while exploring what cell type harbors the mutation, he said.

More information

The National Organization of Vascular Anomalies has more about vascular malformations.



-- Kevin McKeever



SOURCE: Medical College of Wisconsin, news release, Jan. 29, 2009

Last Updated: Jan. 29, 2009

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