Combating Myths About Seasonal Allergies
Herbal Remedy Could Halt Peanut Allergy
Traffic, Dust Linked to Asthma in Kids
Acupuncture Eases Side Effects of Head, Neck Cancer Treatments
Maggots as Good as Gel in Leg Ulcer Treatments
Indigo Ointment Benefits Psoriasis Patients
Rest Easy. When It Comes to Swine Flu, Your Pet Is Safe
'Comfort Dogs' Come to Emotional Rescue
Safe Toys for Dogs
Chronic Low Back Pain Is on the Rise
Get in Step With Summer Foot Care
Study Examines How Rheumatoid Arthritis Destroys Bone
Researchers ID Genetic Markers for Esophageal Cancer
Scams and Shams That Prey on Cancer Patients
Drinking Green Tea May Slow Prostate Cancer
Mom's Smoking May Lead to SIDS
Falls Are Top Cause of Injury, Death Among Elderly
Caring for Aging Loved Ones Can Be a Catch-22
Review Confirms Links Between Diet, Heart Health
Health Tip: Are You Anemic?
Common Antioxidant Might Slow Parkinson's
The Acne Drug Accutane More Than Doubles Depression Risk
Get Sugared!.... Its a sweet choice for hair removal
With Psoriasis, the Internet May Offer Hope
Study Links Osteoporosis Drugs to Jaw Trouble
Acid Drinks Blamed for Increase in Tooth Erosion
Mom's Vitamin D Levels Affect Baby's Dental Health
Arthritis Hits More Than Half of Diabetics
Laughter May Lower Heart Attack Risk in Diabetics
Patients' Photos Help Boost Radiologists' Accuracy
School Meals Need to Get Healthier
Natural Oils Help Lower Body Fat For Some
Drinking Your Way to Health? Perhaps Not
Could Your Cell Phone Help Shield You From Alzheimer's?
Review Finds Marijuana May Help MS Patients
Arsenic in Drinking Water Raises Diabetes Risk
1976 Italian Dioxin Release Damaged Babies' Thyroids
Walkable Neighborhoods Keep the Pounds Off
Glaucoma Treatment Can Prevent Blindness
Eye Problems, Hearing Loss May Be Linked
Protein Might One Day Prevent Blindness
Want to Stop Cancer? You Can, Experts Say
Exercise Helps Reduce Falls in Young and Old
Maximize Your Run
HRT Use Raises Risk of Stomach Trouble
New Yogurt May Ease Stomach Ulcers
Soothing Imagery May Help Rid Some Kids of Stomach Pain
The Yearly Flu Shot Debate
Coffee Cuts Liver Scarring in Hepatitis C
Swine Flu Loves a Crowd
Zen May Thicken Brain, Thwart Pain
Many Children Will Outgrow Headaches
Ski Helmets Encouraged for All
Using Light Therapy to Silence Harmful Brain Activity
'Comfort Dogs' Come to Emotional Rescue
Study Suggests Link Between Cell Phones and Brain Tumors
Noise Hurts Men's Hearing More, Study Shows
Summer Sounds Can Lead to Hearing Loss
Years of Heavy Smoking Raises Heart Risks
Using Light Therapy to Silence Harmful Brain Activity
Chinese Red Yeast Rice May Prevent Heart Attack
Surgical Masks Could Prevent Flu, Maybe
Chinese 'Devil Dung' Plant Could Be a Swine Flu Fighter
Poor Restroom Cleaning Causes Cruise-Ship Sickness
Obesity May Affect Fertility in Young Womene
Play Creatively as a Kid, Be a Healthier Adult
Exercise Eases Obesity and Anger in Kids
Childhood Dairy Intake Boosts Bone Health Later On
Exercise May Prevent Prostate Cancer: Study Shows
Noise Hurts Men's Hearing More, Study Shows
Varicose Veins May Mask Larger Problem
Consciousness Helps the Mind and Body Work Together
Green Spaces Boost the Body and the Mind
Mind Exercise Might Help Stroke Patients
Tai Chi May Help Ease Fibromyalgia
Are We Exercising Pain Away? Not So Much.
Alleviating Rheumatoid Arthritis
Mom's Extra Pregnancy Pounds May Raise Child's Heart Risks
Pre-Pregnancy Weight Linked to Babies' Heart Problems
Exercise Boosts Bone Density in Breast-Feeding Moms
Exercise Helps Reduce Falls in Young and Old
Tai Chi and Qigong Offer Many Health Benefits: Review
15-Point Test Gauges Alzheimer's Risk
6 to 8 Hours of Shut-Eye Is Optimal for Health
Meditation May Help Put Primary Insomnia to Bed
Moderate Aerobics May Ease Insomnia Symptoms
Exercise As Well As Acupuncture, May Ease Polycystic Ovarian Syndrome
Natural Childbirth Moms More Attuned to Babies' Cry
Sugary Colas Tied to Gestational Diabetes
Add your Article

Compound in Red Wine Fights Ravages of Age

By Alan Mozes
HealthDay Reporter

THURSDAY, July 3 (HealthDay News) -- A key compound in red wine known as resveratrol appears to protect against many of the health ravages associated with growing old, new animal research reveals.

"It's very hard to extrapolate from this finding to comment on the benefits of red wine directly, because red wine has many other compounds besides resveratrol, including ethanol, which have very active biological effects," noted study author Rafael de Cabo, unit chief of the laboratory of experimental gerontology at the National Institute on Aging in Baltimore.

"But red wine is a good source of resveratrol," he added. "And, in this mouse study, we have shown that this particular compound has very strong positive effects on preventing cardiovascular disease, reducing heart inflammation, keeping bone health in terms of structure and function, and maintaining loco-motor and balance activity. So, if these effects translate into humans, it will have a very good impact on the standard of human health."

De Cabo conducted the research with David A. Sinclair, of Harvard Medical School. Their team is publishing its findings in the July 3 online issue of Cell Metabolism.

Daily consumption of the compound -- also found in the skin of grapes and the crust of peanuts and walnuts -- broadly improved the long-term quality of life of middle-aged mice, although most mice did not end up living longer.

Nevertheless, the age-defying health benefits of resveratrol closely mimicked those previously associated with rigorous calorie-restricted diets -- raising hopes for simpler and easier means by which to help fight off age-related decline.

The authors noted that prior research has touted the healthy benefits associated with daily caloric restriction of between 30 percent and 50 percent below average, as well as with fasting every other day. Such diets have been linked to a reduction in the risk for age-associated disease and stress, alongside a slowing of age-related functional decline.

"But we can't have half of America going permanently on a diet," said de Cabo. "We just can't do it. It's not practical, and it's not going to happen."

Alternatively, he and his colleagues began to explore the potential of resveratrol -- a compound that has already been shown to extend the lives of yeast, worms, flies and fish.

In initial studies, the team found that consuming the compound did improve the health and survival of obese mice -- despite consuming a high-calorie diet.

To follow up, the researchers now compared the health and life spans of middle-age mice given either a standard diet or a calorie-restricted diet, with or without high or low daily dosages of resveratrol.

De Cabo and his colleagues found that resveratrol had the same positive impact on mouse livers, muscles, hearts and bones as calorie restriction alone.

Regardless of dietary protocol, the general health and vigor of mice on a long-term regimen (approximately one year) of resveratrol improved overall, without apparent side effects. However, only mice consuming resveratrol alongside a high-calorie diet were found to actually live longer.

"This certainly is consistent with previous studies," noted Dr. Edward A. Fisher, a professor of cardiovascular medicine and cell biology at the New York University School of Medicine in New York City. "So, I'm not surprised by the finding."

"But by looking at specific outcomes in specific tissues, this work is certainly more detailed and rigorous," he added. "And it further supports the hypothesis that this compound staves off the effects of aging."

On another food front, researchers out of Athens Medical School in Greece have published a new study in the current issue of the European Journal of Cardiovascular Prevention and Rehabilitation suggesting that drinking green tea is good for the heart.

Consuming green tea, the authors noted, appeared to quickly improve the function of cells that line the circulatory system, known as endothelial cells. Because endothelial cell damage is a key contributor to the onset of atherosclerosis, boosting the performance of such cells could help stave off heart disease.

More information

For additional information on health benefits associated with red wine and resveratrol, visit the Mayo Clinic.

SOURCES: Rafael de Cabo, Ph.D., investigator and unit chief, laboratory of experimental gerontology, National Institute on Aging, Baltimore; Edward A. Fisher, M.D., Ph.D., professor, cardiovascular medicine and cell biology, New York University School of Medicine, New York City; July 3, 2008, Cell Metabolism, online

Last Updated: July 03, 2008

Copyright 2008 ScoutNews, LLC. All rights reserved.

More articles at