ALLERGY, RESPIRATORY
Herbal Remedy Could Halt Peanut Allergy
Keep Asthma, Allergies at Bay for the Holidays
Asthmatics Who Quit Smoking May Reverse Lung Damage
ALTERNATIVE MEDICINE
Alternative Treatments May Boost IVF Success
Pharoah's Wine Jar Yields Medicinal Secrets
Regular Yoga May Improve Eating Habits
ANIMAL CARE
Animals Respond to Acupuncture's Healing Touch
Rest Easy. When It Comes to Swine Flu, Your Pet Is Safe
'Comfort Dogs' Come to Emotional Rescue
BONES & JOINTS
Almost Half of Adults Will Develop Knee Osteoarthritis by 85
Arthritis Hits More Than Half of Diabetics
Osteoporosis May Raise Risk for Vertigo
CANCER
Red Meat No No No But Oily Fish Yes Yes Yes
Method for Treating Cervical Lesions May Pose Pregnancy Risks
Smokeout '08: The Perfect Time to Quit
CAREGIVING
Depression, PTSD Common Among Lung Transplant Patient Caregivers
Falls Are Top Cause of Injury, Death Among Elderly
Birthmark or Blood Vessel Problem?
CIRCULATORY SYSTEM
Support Network May Play Role in Benefits of Drinking
Varicose Veins May Mask Larger Problem
Years of Exposure to Traffic Pollution Raises Blood Pressure
COSMETIC
Health Tip: After Liposuction
With Psoriasis, the Internet May Offer Hope
What to Do If You Have Unsightly Veins
DENTAL, ORAL
An Oral Approach to Heart Disease
Toothbrushing May Stave Off Heart Woes
Acupuncture May Ease Anxiety Over Dental Work
DIABETES
Arthritis Hits More Than Half of Diabetics
Poor Blood Sugar Control After Heart Surgery Impacts Outcomes
Boosting Vitamin D Can Do a Heart Good
DIET, NUTRITION
Meat Additives May Be Dangerous for Kidney Patients
Just Say No to Nuts During Pregnancy
Most Fast-Food French Fries Cooked in Unhealthiest Oil
DISABILITIES
Review Finds Marijuana May Help MS Patients
Could Your Cell Phone Help Shield You From Alzheimer's?
ENVIRONMENTAL HEALTH
FDA Faulted for Stance on Chemical in Plastics
Pesticides Linked to Parkinson's
Childhood Food Allergies on the Rise
EYE CARE, VISION
Americans Losing Sight of Eye Health
Eye Care Checkups Tied to Insurance Status
Certain Diabetes Drugs May Pose Eye Risk
FITNESS
Go To Work But Skip The Car
Be Healthy, Spend Less
Walking Golf Course Affects Swing, Performance
GASTROINTESTINAL PROBLEMS
Peppermint Oil, Fiber Can Fight Irritable Bowel
Japanese Herbals May Ease Gastro Woes
Intestinal Bacteria Trigger Immune Response
GENERAL HEALTH
Hidden Salt in Diet Haunts Many With Heart Failure
'Soda Tax' Wins Health Experts' Support
Eating Nuts May Help Cholesterol Levels
HEAD & NECK
Zen May Thicken Brain, Thwart Pain
Ski Helmets Encouraged for All
Many Children Will Outgrow Headaches
HEALTH & TECHNOLOGY
'Cell Phone Elbow' -- A New Ill for the Wired Age
Magnet Therapy May Ease Hard-to-Treat Depression
Airport Full Body Scanners Pose No Health Threat: Experts
HEARING
Noise Hurts Men's Hearing More, Study Shows
Summer Sounds Can Lead to Hearing Loss
HEART & CARDIOVASCULAR
Cherry-Enriched Diet Cut Heart Risks in Rats
Omega-6 Fatty Acids Can Be Good for You
Fewer Heart Attacks After England Goes Smoke-Free
INFECTIOUS DISEASE
Hand Washing 10 Times a Day May Help Keep Flu Away
The HPV Vaccine: Preventative Medicine or Human Sacrifice?
Poor Restroom Cleaning Causes Cruise-Ship Sickness
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
Better Sleep, Grades Seem to Go Up
Working Intensely Early on May Help Autistic Kids
Eating Fish, Breast-Feeding Boost Infant Development
MEN'S HEALTH
Strenuous Daily Workout May Keep Cancer at Bay
Drinking Green Tea May Slow Prostate Cancer
Countdown to Hair Loss
MENTAL HEALTH
Music Soothes Anxiety as Well as Massage Does
Cinnamon Breaks Up Brain Plaques, May Hold Key to Fighting Alzheimer’s
Memory Loss Help from Brain Supplement Prevagen
PAIN
Are We Exercising Pain Away? Not So Much.
'Cell Phone Elbow' -- A New Ill for the Wired Age
Tai Chi May Help Ease Fibromyalgia
PHYSICAL THERAPY
PREGNANCY
Sleeping Could Help Women Lose The Baby Fat
Calcium Supplements Cut Blood Lead Levels During Pregnancy
Woman in America Are Delaying Motherhood, Study Says
SENIORS
A Little Alcohol May Stave Off Alzheimer's
Living Alone Increases Odds of Developing Dementia
Keeping Mentally Active Seems To Keep The Brain Active
SEXUAL HEALTH
SLEEP DISORDERS
Better Sleep, Grades Seem to Go Up
Sleeping Could Help Women Lose The Baby Fat
6 to 8 Hours of Shut-Eye Is Optimal for Health
WOMEN'S HEALTH
Women Who Run May Benefit From Extra Folic Acid
Caffeine in Pregnancy Associated With Low Birth Weight Risk
Acupuncture May Relieve Acid Indigestation In Pregnancy
Add your Article

Fatty Acid in Olive Oil Wards Off Hunger

By Kathleen Doheny
HealthDay Reporter

TUESDAY, Oct. 7 (HealthDay News) -- A fatty acid found in olive oil and other heart-healthy monounsaturated fats wards off hunger pangs, a new study suggests.

The findings might one day lead to the development of new drugs to limit, or even enhance, appetite, the researchers said.

Daniele Piomelli, a professor of pharmacology at the University of California, Irvine, and his colleagues infused the fat -- called oleic acid -- into the intestines of laboratory rodents and found that it was converted into a fat messenger called oleoylethanolamide (OEA).

"This OEA activates a receptor protein causing a specific type of satiety," Piomelli said. "This protein initiates a series of physiological events that lead to activation of nerves in the intestine."

The result: A message goes up to the brain and tells the body, in effect, that it's full. "This is different than compounds that make you eat less at a given meal," he said.

Piomelli and his team surgically infused the fat directly into the animals' intestines, then measured appetite. "The animals eat less," he said.

To further test the mechanism, they injected the fat into mice altered so they couldn't make OEA. "When you infuse the fat into these mice, they don't get the decreased hunger," he said.

The practical application? To someday make a drug that would slow OEA from being broken down in the body, thus extending the feeling of fullness. Likewise, OEA levels might be adjusted to help people who have decreased appetite, Piomelli said.

The findings are published in the October issue of Cell Metabolism.

Roger Clemens, director of regulatory science at the University of Southern California School of Pharmacy and a spokesman for the Institute of Food Technologists, said, "From a basic science perspective, it [the new study] is fascinating. It shows the importance of oleic acid."

And while the new research confirms previous work, Clemens said the practical applications remain in the future.

But he added this caution: Eating extra olive oil isn't a route to curbing hunger. While considered a heart-healthy fat, it contains calories that can add up quickly.

More information

For more on olive oil, visit the American Dietetic Association.



SOURCES: Daniele Piomelli, Ph.D., professor, pharmacology, University of California, Irvine, and director, Unit of Drug Discovery and Development, Italian Institute of Technology, Genoa, Italy; Roger Clements, Dr.P.H., spokesman, Institute of Food Technologists, and director, regulatory science, and professor, School of Pharmacology, University of Southern California, Los Angeles; October 2008 Cell Metabolism

Last Updated: Oct. 07, 2008

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