ALLERGY, RESPIRATORY
Asthmatics Who Quit Smoking May Reverse Lung Damage
'Safe' Ozone Levels May Not Be for Some
Herbal Remedy Could Halt Peanut Allergy
ALTERNATIVE MEDICINE
Indigo Ointment Benefits Psoriasis Patients
Memory Loss Help from Brain Supplement Prevagen
Ginkgo No Shield Against Alzheimer's
ANIMAL CARE
'Comfort Dogs' Come to Emotional Rescue
Safe Toys for Dogs
Rest Easy. When It Comes to Swine Flu, Your Pet Is Safe
BONES & JOINTS
Vitamin D Plus Calcium Guards Against Fractures
In Elderly Women, Hip Fractures Often Follow Arm Breaks
Breast-feeding Might Shield Women From Rheumatoid Arthritis
CANCER
Healthy Behaviors Slow Functional Decline After Cancer
Poor Women Seem to Be Skipping Breast Cancer Drugs
Meditation May Reduce Stress in Breast Cancer Patients
CAREGIVING
With Age Comes Greater Risk of Hypothermia
High Rate of Rehospitalizations Costing Billions
For Dialysis Patients, More Pills = Lower Quality of Life
CIRCULATORY SYSTEM
Varicose Veins May Mask Larger Problem
Grapefruit-Heavy Diet Helped Spur Dangerous Clot
Health Tip: Are You Anemic?
COSMETIC
Study Evaluates Laser Therapies for Hair Removal
Mouse Study Finds Molecule That Tells Hair to Grow
Wrinkle Fillers Need Better Label Warnings: FDA Panel
DENTAL, ORAL
Gum Disease Might Boost Cancer Risk
Most Insured Adults Worry About Health Care Costs: Poll
An Oral Approach to Heart Disease
DIABETES
Study Shows Turmeric May Prevent Type 2 Diabetes
Patients' Photos Help Boost Radiologists' Accuracy
Spices, Herbs Boost Health for Diabetics
DIET, NUTRITION
Red Meat No No No But Oily Fish Yes Yes Yes
Mercury in Fish Linked to High Blood Pressure
Adding Garlic Might Cut Cancer Risk
DISABILITIES
Could Your Cell Phone Help Shield You From Alzheimer's?
Review Finds Marijuana May Help MS Patients
ENVIRONMENTAL HEALTH
Stomach Germ May Protect Against Asthma
Exhaust From Railroad Diesel Linked to Lung Ailments
Staying Slim Is Good for the Environment
EYE CARE, VISION
Just Like Skin, Eyes Can 'Burn' in Strong Sun
Kids Who Spend More Time Outdoors Have Better Vision
Eye Disease, Cognitive Decline Linked in Study
FITNESS
Go To Work But Skip The Car
Vigorous Treadmill Workout Curbs Appetite Hormones
Moderate Aerobic Exercise Lowers Diabetics' Liver Fat
GASTROINTESTINAL PROBLEMS
New Guidelines Issued for Management of IBS
Japanese Herbals May Ease Gastro Woes
Gum Chewing May Speed Colon Surgery Recovery
GENERAL HEALTH
Week of Historic Senate Hearings on Integrative Medicine May Open New Doors
Whole Grains, Bran May Fight Hypertension in Men
Life Expectancy in U.S. Hits New High
HEAD & NECK
Ski Helmets Encouraged for All
Zen May Thicken Brain, Thwart Pain
Many Children Will Outgrow Headaches
HEALTH & TECHNOLOGY
Subway Defibrillators Save Lives
'Comfort Dogs' Come to Emotional Rescue
Save Your Aging Brain, Try Surfing The Web
HEARING
Summer Sounds Can Lead to Hearing Loss
Noise Hurts Men's Hearing More, Study Shows
HEART & CARDIOVASCULAR
Vitamin B3 May Help Repair Brain After a Stroke
Man's Best Friend Helps Mend Broken Hearts
Cocoa in Chocolate May Be Good for the Heart
INFECTIOUS DISEASE
Poor Restroom Cleaning Causes Cruise-Ship Sickness
Grapefruit Compound Inhibits Hepatitis C Virus
Viral Infection Might Trigger High Blood Pressure
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
Fussy Babys Could Be Out Of Your Control
Meaningful Conversations Boost Kids' Language Skills
Backpack Safety Should Be on Back-to-School Lists
MEN'S HEALTH
Strenuous Daily Workout May Keep Cancer at Bay
The Dark Side of Vegetarianism
Vigorous Exercise Cuts Stroke Risk for Men, Not Women
MENTAL HEALTH
A Simple 'Thank You' Brings Rewards to All
Drink Away Dementia?
Meditation, Yoga Might Switch Off Stress Genes
PAIN
Alleviating Rheumatoid Arthritis
Are We Exercising Pain Away? Not So Much.
Tai Chi May Help Ease Fibromyalgia
PHYSICAL THERAPY
PREGNANCY
Acupuncture May Ease Depression During Pregnancy
Expectant Mom's Exercise Keeps Newborn's Birth Weight Down
Exercise As Well As Acupuncture, May Ease Polycystic Ovarian Syndrome
SENIORS
Seniors Cope With Sleep Loss Better Than Young Adults
Martial Arts Training May Save Seniors' Hips
Want Better Health in the New Year, Add Exercise to Your Day
SEXUAL HEALTH
SLEEP DISORDERS
Meditation May Help Put Primary Insomnia to Bed
Pay Attention to Signs That Say You're Too Fatigued to Drive
Daylight Savings: Not a Bright Time for All
WOMEN'S HEALTH
Active Young Women Need Calcium, Vitamin D
Heal Your Life® Tips for Living Well
Women Who Run May Benefit From Extra Folic Acid
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High Temps Degrade Contact Lens Solution: Study

MONDAY, Nov. 10 (HealthDay News) -- Prolonged exposure to high temperatures degrades the antifungal properties of the ReNu with MoistureLoc contact lens solution, which was implicated in a U.S. eye infection outbreak between 2004 and 2006, a new study says.

ReNu with MoistureLoc contains a microbial agent not found in other contact lens solutions. Between August 2004 and March 2006, there were 154 confirmed cases of the eye infection Fusarium keratitis among users of ReNu with MoistureLoc, made by Bausch & Lomb, the study authors said.

The U.S. Food and Drug Administration cited the company for inadequate temperature control in the production, storage and transport of ReNu with MoistureLoc produced at Bausch & Lomb's Greenville, S.C., plant.

In the new study, Dr. John D. Bullock, of the Wright State University Boonshoft School of Medicine in Dayton, Ohio, and colleagues conducted tests on ReNu with MoistureLoc and five other contact lens solutions.

"Two bottles of each solution were separately stored at room temperature and 60 degrees Celsius (140 degrees Fahrenheit) for four weeks, serially diluted and then tested for their ability to inhibit growth of 11 Fusariam isolates [seven of which were associated with the keratitis epidemic]," the researchers wrote.

Compared to the other solutions, ReNu with MoistureLoc showed the greatest decline in antifungal activity when stored at 60 degrees C. Clear Care and ReNu MultiPlus performed the best, the researchers said.

When the researchers focused on the strains of Fusariam associated with the keratitis outbreak, ReNu with MoistureLoc allowed fungal growth in 27 of 84 combinations when stored at room temperature and in 67 of 84 combinations when stored at 60 degrees C.

The study was published in the November issue of the Archives of Ophthalmology.

"The precise temperature, duration of exposure to elevated temperature and extent of temperature fluctuation that may diminish the antimicrobial activity of a particular contact lens solution is not known, and thus, additional studies may be warranted. However, our findings, coupled with the FDA reports of Bausch & Lomb's failure to regulate the storage and transport temperatures of the products manufactured in their Greensville plant, may be significant," the study authors concluded.

"Knowledge of the potential loss of antimicrobial activity of contact lens solutions and other pharmaceutical products when exposed to higher temperatures and the risk of such exposure when storing and transporting those products may help prevent such epidemics in the future," the researchers added.

More information

The U.S. Food and Drug Administration has more about contact lenses and eye infections.



-- Robert Preidt



SOURCE: JAMA/Archives journals, news release, Nov. 10, 2008

Last Updated: Nov. 10, 2008

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