ALLERGY, RESPIRATORY
Molecule in Skin May Link Eczema and Asthma
Folic Acid Might Offer Allergy Relief
Know Your Asthma Triggers
ALTERNATIVE MEDICINE
Ginkgo No Shield Against Alzheimer's
Eight Spiritual Universal Principles in the Art of Practice
Placebo Acupuncture Tied to Higher IVF Pregnancies
ANIMAL CARE
Rest Easy. When It Comes to Swine Flu, Your Pet Is Safe
Animals Respond to Acupuncture's Healing Touch
Safe Toys for Dogs
BONES & JOINTS
Alleviating Rheumatoid Arthritis
B Cells Can Act Alone in Autoimmune Diseases
Soccer's a Winner for Building Bone Health in Girls
CANCER
Vitamin D May Improve Melanoma Survival
Vitamin C Shows Promise as Cancer Treatment
Some Spices Cut Cancer Risk That Comes With Grilled Burgers
CAREGIVING
Moms Who Breast-Feed Less Likely to Neglect Child
3 Steps Might Help Stop MRSA's Spread
MRSA Infections Spreading to Kids in Community
CIRCULATORY SYSTEM
An Apple a Day May Help Keep Heart Disease Away
Firefighters Have Narrower-Than-Normal Arteries, Study Finds
Laughter Can Boost Heart Health
COSMETIC
Health Tip: After Liposuction
The Acne Drug Accutane More Than Doubles Depression Risk
What to Do If You Have Unsightly Veins
DENTAL, ORAL
Dental Implants Need More Work Than Root Canals
Biological Product Shows Promise Against Gum Disease
Gum Disease May Reactivate AIDS Virus
DIABETES
'Standard' Glucose Test May Be Wrong One for Obese Children
Study Shows Turmeric May Prevent Type 2 Diabetes
Laughter May Lower Heart Attack Risk in Diabetics
DIET, NUTRITION
Healthy Eating While On Vacation
Imagine Food Aromas That Prevent Overeating
Eating your way to Good Health
DISABILITIES
Could Your Cell Phone Help Shield You From Alzheimer's?
Review Finds Marijuana May Help MS Patients
ENVIRONMENTAL HEALTH
Disinfectants Can Boost Bacteria's Resistance to Treatment
Are Medical Meetings Environmentally Unfriendly?
'Safe' Ozone Levels May Not Be for Some
EYE CARE, VISION
Glaucoma Treatment Can Prevent Blindness
Thyroid Problems Boost Glaucoma Risk
Glaucoma Associated With Reading Impairments in Elderly
FITNESS
Keep Safety in Mind While Your Kids Are Cooling Off in the Water
Basketball Star Details His Struggle With Gout
Living With Less TV, More Sweat Boosts Weight Loss
GASTROINTESTINAL PROBLEMS
Intestinal Bacteria Trigger Immune Response
Soothing Imagery May Help Rid Some Kids of Stomach Pain
Peppermint Oil, Fiber Can Fight Irritable Bowel
GENERAL HEALTH
How Weight Loss Can Help the Heart
Life Expectancy in U.S. Hits New High
More Medicinal Uses for Pomegranate
HEAD & NECK
Zen May Thicken Brain, Thwart Pain
Many Children Will Outgrow Headaches
Ski Helmets Encouraged for All
HEALTH & TECHNOLOGY
Using Light Therapy to Silence Harmful Brain Activity
Airport Full Body Scanners Pose No Health Threat: Experts
E-Mailing Your Way to Healthier Habits
HEARING
Summer Sounds Can Lead to Hearing Loss
Noise Hurts Men's Hearing More, Study Shows
HEART & CARDIOVASCULAR
Soy Protein Doesn't Lower Cholesterol
Quitting Smoking Doubles Survival in Early Stage Lung Cancer
Boosting Vitamin D Can Do a Heart Good
INFECTIOUS DISEASE
Surgical Masks Could Prevent Flu, Maybe
Grapefruit Compound Inhibits Hepatitis C Virus
Older Adults May Have Some Immunity to Swine Flu
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
Time to Remind Teens About Sun Protection
Plastics Chemical Tied to Aggression in Young Girls
Teen Internet Addicts More Likely to Self-Harm: Study
MEN'S HEALTH
Whole Grains, Bran May Fight Hypertension in Men
The Dark Side of Vegetarianism
Varicose Veins May Mask Larger Problem
MENTAL HEALTH
Chocolate a Sweet Pick-Me-Up for the Depressed
Environmental Chemicals May Affect Male Reproduction
Musicians' Brains Tuned to Emotions in Sound
PAIN
Acupuncture, Real or Fake, Eases Back Pain
Are We Exercising Pain Away? Not So Much.
Alleviating Rheumatoid Arthritis
PHYSICAL THERAPY
PREGNANCY
Obesity May Affect Fertility in Young Womene
Placebo Acupuncture Tied to Higher IVF Pregnancies
Pre-Pregnancy Weight Linked to Babies' Heart Problems
SENIORS
Tai Chi and Qigong Offer Many Health Benefits: Review
Seniors Cope With Sleep Loss Better Than Young Adults
For Older Walkers, Faster Is Better
SEXUAL HEALTH
SLEEP DISORDERS
Pay Attention to Signs That Say You're Too Fatigued to Drive
Lose Weight, Sleep Apnea May Improve
Exercising Throat Muscles May Relieve Sleep Apnea
WOMEN'S HEALTH
Calcium Helps Ward Off Colon Cancer
Flame-Retardant Chemical Linked to Conception Problems
Acupuncture May Help Relieve Polycystic Ovary Syndrome
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High Temps Degrade Contact Lens Solution: Study

MONDAY, Nov. 10 (HealthDay News) -- Prolonged exposure to high temperatures degrades the antifungal properties of the ReNu with MoistureLoc contact lens solution, which was implicated in a U.S. eye infection outbreak between 2004 and 2006, a new study says.

ReNu with MoistureLoc contains a microbial agent not found in other contact lens solutions. Between August 2004 and March 2006, there were 154 confirmed cases of the eye infection Fusarium keratitis among users of ReNu with MoistureLoc, made by Bausch & Lomb, the study authors said.

The U.S. Food and Drug Administration cited the company for inadequate temperature control in the production, storage and transport of ReNu with MoistureLoc produced at Bausch & Lomb's Greenville, S.C., plant.

In the new study, Dr. John D. Bullock, of the Wright State University Boonshoft School of Medicine in Dayton, Ohio, and colleagues conducted tests on ReNu with MoistureLoc and five other contact lens solutions.

"Two bottles of each solution were separately stored at room temperature and 60 degrees Celsius (140 degrees Fahrenheit) for four weeks, serially diluted and then tested for their ability to inhibit growth of 11 Fusariam isolates [seven of which were associated with the keratitis epidemic]," the researchers wrote.

Compared to the other solutions, ReNu with MoistureLoc showed the greatest decline in antifungal activity when stored at 60 degrees C. Clear Care and ReNu MultiPlus performed the best, the researchers said.

When the researchers focused on the strains of Fusariam associated with the keratitis outbreak, ReNu with MoistureLoc allowed fungal growth in 27 of 84 combinations when stored at room temperature and in 67 of 84 combinations when stored at 60 degrees C.

The study was published in the November issue of the Archives of Ophthalmology.

"The precise temperature, duration of exposure to elevated temperature and extent of temperature fluctuation that may diminish the antimicrobial activity of a particular contact lens solution is not known, and thus, additional studies may be warranted. However, our findings, coupled with the FDA reports of Bausch & Lomb's failure to regulate the storage and transport temperatures of the products manufactured in their Greensville plant, may be significant," the study authors concluded.

"Knowledge of the potential loss of antimicrobial activity of contact lens solutions and other pharmaceutical products when exposed to higher temperatures and the risk of such exposure when storing and transporting those products may help prevent such epidemics in the future," the researchers added.

More information

The U.S. Food and Drug Administration has more about contact lenses and eye infections.



-- Robert Preidt



SOURCE: JAMA/Archives journals, news release, Nov. 10, 2008

Last Updated: Nov. 10, 2008

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