ALLERGY, RESPIRATORY
Air Quality Better in Northeast, Midwest
Air Pollution May Raise Blood Pressure
Asthmatics Who Quit Smoking May Reverse Lung Damage
ALTERNATIVE MEDICINE
Licorice May Block Absorption of Organ Transplant Drug
Insight on Herbals Eludes Doctors, Patients Alike
Tai Chi: An Ideal Exercise for Many People with Diabetes
ANIMAL CARE
Separation Anxiety, Canine-Style
'Comfort Dogs' Come to Emotional Rescue
Rest Easy. When It Comes to Swine Flu, Your Pet Is Safe
BONES & JOINTS
Rheumatoid Arthritis Hits Women Harder
Human Ancestors Put Best Foot Forward 1.5M Years Ago
Arthritis Hits More Than Half of Diabetics
CANCER
U.S. Reported 25,000 Cases of HPV-Related Cancers Annually
Asthmatics Who Quit Smoking May Reverse Lung Damage
Gene Studies Reveal Cancer's Secrets
CAREGIVING
Birthmark or Blood Vessel Problem?
Critically Ill Patients Lack Vitamin D
Newborn Screenings Now Required Across U.S.
CIRCULATORY SYSTEM
High Blood Fat Levels Common in Americans
Walk 100 Steps a Minute for 'Moderate' Exercise
Years of Exposure to Traffic Pollution Raises Blood Pressure
COSMETIC
Contact Lenses Boost Kids' Self-Image
Gum Chewing May Cut Craving for Snacks
What to Do If You Have Unsightly Veins
DENTAL, ORAL
An Oral Approach to Heart Disease
Scientists Find Gene for Tooth Enamel
Gum Care Helps Control Type 2 Diabetes and Its Complications
DIABETES
Arthritis Hits More Than Half of Diabetics
24 Million Americans Had Diabetes in 2007
Coffee, Tea Might Stave Off Diabetes
DIET, NUTRITION
Six Healthy-Sounding Foods That Really Aren't
Red Meat No No No But Oily Fish Yes Yes Yes
'Soda Tax' Wins Health Experts' Support
DISABILITIES
Could Your Cell Phone Help Shield You From Alzheimer's?
Review Finds Marijuana May Help MS Patients
ENVIRONMENTAL HEALTH
Vitamin D Deficit May Trigger MS Risk Gene
Small Doses of Carbon Monoxide Might Help Stroke Victims
Improved Fungicides May Be Easier on Environment
EYE CARE, VISION
Protein Might One Day Prevent Blindness
Unconscious Learning: In the Eye of the Beholder?
Nearly 18 Million Will Have Macular Degeneration by 2050
FITNESS
Yoga Can Ease Lower Back Pain
Tai Chi and Qigong Offer Many Health Benefits: Review
Mom and Baby Alike May Benefit From Exercise
GASTROINTESTINAL PROBLEMS
Peppermint Oil, Fiber Can Fight Irritable Bowel
Gum Chewing May Speed Colon Surgery Recovery
Intestinal Bacteria Trigger Immune Response
GENERAL HEALTH
How Weight Loss Can Help the Heart
Keep Safety in Mind While Your Kids Are Cooling Off in the Water
Can You Talk Your Way to Happy?
HEAD & NECK
Ski Helmets Encouraged for All
Many Children Will Outgrow Headaches
Zen May Thicken Brain, Thwart Pain
HEALTH & TECHNOLOGY
'Cell Phone Elbow' -- A New Ill for the Wired Age
Study Suggests Link Between Cell Phones and Brain Tumors
Save Your Aging Brain, Try Surfing The Web
HEARING
Summer Sounds Can Lead to Hearing Loss
Noise Hurts Men's Hearing More, Study Shows
HEART & CARDIOVASCULAR
Laughter Can Boost Heart Health
Dark Chocolate May Lower Stroke Risk
More Steps a Day Lead to Better Health
INFECTIOUS DISEASE
Viral Infection Might Trigger High Blood Pressure
Grapefruit Compound Inhibits Hepatitis C Virus
Chinese 'Devil Dung' Plant Could Be a Swine Flu Fighter
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
Safety Should Be Priority for Those Involved in Kids' Sports
Scorpion Anti-Venom Speeds Children's Recovery
Bullying Seems to Affect Kids Years Later
MEN'S HEALTH
Sunlight May Help Protect Men From Kidney Cancer
Eating Fast Until Full Triples Overweight Risk
More Vitamin C May Mean Less Chance of Gout
MENTAL HEALTH
Green Spaces Boost the Body and the Mind
Eight Spiritual Universal Principles in the Art of Practice
Man's Best Friend Helps Mend Broken Hearts
PAIN
Acupuncture, Real or Fake, Eases Back Pain
Are We Exercising Pain Away? Not So Much.
'Cell Phone Elbow' -- A New Ill for the Wired Age
PHYSICAL THERAPY
PREGNANCY
Acupuncture May Relieve Acid Indigestation In Pregnancy
Prenatal Stress May Boost Baby's Asthma Risk
Obesity May Affect Fertility in Young Womene
SENIORS
Tai Chi May Help Ease Fibromyalgia
Common Antioxidant Might Slow Parkinson's
Older Adults May Have Some Immunity to Swine Flu
SEXUAL HEALTH
SLEEP DISORDERS
Lose Weight, Sleep Apnea May Improve
6 to 8 Hours of Shut-Eye Is Optimal for Health
Better Sleep, Grades Seem to Go Up
WOMEN'S HEALTH
Women Smokers Lose 14.5 Years Off Life Span
Postmenopausal Women With Breast Cancer Face Joint Issues
Natural Therapies for Menopause
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High Temps Degrade Contact Lens Solution: Study

MONDAY, Nov. 10 (HealthDay News) -- Prolonged exposure to high temperatures degrades the antifungal properties of the ReNu with MoistureLoc contact lens solution, which was implicated in a U.S. eye infection outbreak between 2004 and 2006, a new study says.

ReNu with MoistureLoc contains a microbial agent not found in other contact lens solutions. Between August 2004 and March 2006, there were 154 confirmed cases of the eye infection Fusarium keratitis among users of ReNu with MoistureLoc, made by Bausch & Lomb, the study authors said.

The U.S. Food and Drug Administration cited the company for inadequate temperature control in the production, storage and transport of ReNu with MoistureLoc produced at Bausch & Lomb's Greenville, S.C., plant.

In the new study, Dr. John D. Bullock, of the Wright State University Boonshoft School of Medicine in Dayton, Ohio, and colleagues conducted tests on ReNu with MoistureLoc and five other contact lens solutions.

"Two bottles of each solution were separately stored at room temperature and 60 degrees Celsius (140 degrees Fahrenheit) for four weeks, serially diluted and then tested for their ability to inhibit growth of 11 Fusariam isolates [seven of which were associated with the keratitis epidemic]," the researchers wrote.

Compared to the other solutions, ReNu with MoistureLoc showed the greatest decline in antifungal activity when stored at 60 degrees C. Clear Care and ReNu MultiPlus performed the best, the researchers said.

When the researchers focused on the strains of Fusariam associated with the keratitis outbreak, ReNu with MoistureLoc allowed fungal growth in 27 of 84 combinations when stored at room temperature and in 67 of 84 combinations when stored at 60 degrees C.

The study was published in the November issue of the Archives of Ophthalmology.

"The precise temperature, duration of exposure to elevated temperature and extent of temperature fluctuation that may diminish the antimicrobial activity of a particular contact lens solution is not known, and thus, additional studies may be warranted. However, our findings, coupled with the FDA reports of Bausch & Lomb's failure to regulate the storage and transport temperatures of the products manufactured in their Greensville plant, may be significant," the study authors concluded.

"Knowledge of the potential loss of antimicrobial activity of contact lens solutions and other pharmaceutical products when exposed to higher temperatures and the risk of such exposure when storing and transporting those products may help prevent such epidemics in the future," the researchers added.

More information

The U.S. Food and Drug Administration has more about contact lenses and eye infections.



-- Robert Preidt



SOURCE: JAMA/Archives journals, news release, Nov. 10, 2008

Last Updated: Nov. 10, 2008

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