ALLERGY, RESPIRATORY
Combating Myths About Seasonal Allergies
Childhood Food Allergies on the Rise
Using Music and Sports to Improve Kids' Asthma
ALTERNATIVE MEDICINE
Green Tea May Help Brain Cope With Sleep Disorders
Meditation, Yoga Might Switch Off Stress Genes
Indigo Ointment Benefits Psoriasis Patients
ANIMAL CARE
'Comfort Dogs' Come to Emotional Rescue
Animals Respond to Acupuncture's Healing Touch
Separation Anxiety, Canine-Style
BONES & JOINTS
Sea Worm Inspires Novel Bone Glue
Most Kids With Type 1 Diabetes Lack Vitamin D
Almost Half of Adults Will Develop Knee Osteoarthritis by 85
CANCER
U.S. Reported 25,000 Cases of HPV-Related Cancers Annually
Green Tea Compound Slowed Chronic Lymphocytic Leukemia
Vitamin D Good for Breast Cancer Patients
CAREGIVING
Distance No Bar to Kidney Transplants in Remote Areas
Baby's Sleep Position May Not Affect Severity of Head Flattening
Many Hospital Patients Can't ID Their Doctors
CIRCULATORY SYSTEM
Drink a Little Wine, Live a Little Longer
Firefighters Have Narrower-Than-Normal Arteries, Study Finds
Mercury in Fish Linked to High Blood Pressure
COSMETIC
Wrinkle Fillers Need Better Label Warnings: FDA Panel
Mouse Study Finds Molecule That Tells Hair to Grow
The Acne Drug Accutane More Than Doubles Depression Risk
DENTAL, ORAL
Most Insured Adults Worry About Health Care Costs: Poll
Toothbrushing May Stave Off Heart Woes
Gum Disease Might Boost Cancer Risk
DIABETES
Exercise Protects Black Women From Type 2 Diabetes
Boosting Vitamin D Can Do a Heart Good
Treatment for Type 2 Diabetes Updated
DIET, NUTRITION
For Fitness, Cutting Calories May Not Be Enough
More Educated Choose Healthier Foods, But Pay More
Antioxidant-Rich Foods Lose Nutritional Luster Over Time
DISABILITIES
Review Finds Marijuana May Help MS Patients
Could Your Cell Phone Help Shield You From Alzheimer's?
ENVIRONMENTAL HEALTH
Pesticides on Produce Tied to ADHD in Children
Heavy Traffic Can Be Heartbreaking
What's Cookin'? It Could Be Air Pollution
EYE CARE, VISION
FDA Goes After Unapproved Eye Washes, Skin Ointments
It's a Whole New Outlook for Cataract Patients
Kids Who Spend More Time Outdoors Have Better Vision
FITNESS
Want to Stop Cancer? You Can, Experts Say
Being Active an Hour a Day Puts Brakes on Weight Gain
Vigorous Exercise Can Cut Breast Cancer Risk
GASTROINTESTINAL PROBLEMS
HRT Use Raises Risk of Stomach Trouble
New Guidelines Issued for Management of IBS
Japanese Herbals May Ease Gastro Woes
GENERAL HEALTH
Hoping for a Happy Family Holiday? Here's How
More Whole Grains May Mean Less Fat
Laugh and the World Understands
HEAD & NECK
Ski Helmets Encouraged for All
Zen May Thicken Brain, Thwart Pain
Many Children Will Outgrow Headaches
HEALTH & TECHNOLOGY
Imaging Sheds Light on How Acupuncture Works
E-Mailing Your Way to Healthier Habits
'Comfort Dogs' Come to Emotional Rescue
HEARING
Summer Sounds Can Lead to Hearing Loss
Noise Hurts Men's Hearing More, Study Shows
HEART & CARDIOVASCULAR
Western Diet Linked To Heart Disease, Metabolic Syndrome
Kids With Vitamin D Deficiency Linked to Heart Trouble
Years of Heavy Smoking Raises Heart Risks
INFECTIOUS DISEASE
Swine Flu Loves a Crowd
The HPV Vaccine: Preventative Medicine or Human Sacrifice?
Hand Washing 10 Times a Day May Help Keep Flu Away
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
St. John's Wort Doesn't Work for ADHD
Standard IQ Test May Underestimate People With Autism
Pool Chemicals Raise Kids Allergy, Asthma Risk
MEN'S HEALTH
Lots of Sex May Prevent Erectile Dysfunction
Vigorous Exercise Cuts Stroke Risk for Men, Not Women
Noise Hurts Men's Hearing More, Study Shows
MENTAL HEALTH
Green Spaces Boost the Body and the Mind
Eight Spiritual Universal Principles in the Art of Practice
Keeping Mentally Active Seems To Keep The Brain Active
PAIN
Alleviating Rheumatoid Arthritis
Tai Chi May Help Ease Fibromyalgia
Are We Exercising Pain Away? Not So Much.
PHYSICAL THERAPY
PREGNANCY
Prenatal Stress May Boost Baby's Asthma Risk
Exercise Boosts Bone Density in Breast-Feeding Moms
Pregnant Women Exposed To Certain Pollutants Could Lower Childs IQ
SENIORS
Daily dose of beet juice promotes brain health in older adults
For a Healthier Retirement, Work a Little
Mediterranean Diet Plus Exercise Lowers Alzheimer's Risk
SEXUAL HEALTH
SLEEP DISORDERS
Sleeping Could Help Women Lose The Baby Fat
Daylight Savings: Not a Bright Time for All
Pay Attention to Signs That Say You're Too Fatigued to Drive
WOMEN'S HEALTH
Pre-Pregnancy Weight Linked to Babies' Heart Problems
For Women, Moderate Midlife Drinking Linked to Healthier Old Age
Occaisonal Dieting May Cut Breast Cancer, Study Says
Add your Article

New Spray Could Benefit Cystic Fibrosis Patients

MONDAY, May 18 (HealthDay News) -- A new aerosol spray may help keep the airways of cystic fibrosis patients moist and clear, researchers say.

Using a special agent called GS-9411, the spray prevents sodium from being absorbed too quickly, which is a common problem for people with cystic fibrosis. The quick absorption of sodium from the surface of the airway causes their airways to dry, and allows mucous and bacteria to accumulate.

In tests on airway surface cells grown in a laboratory, GS-9411 helped the cells retain moisture for more than eight hours while tests on animals found the spray helped clear excessive mucus for at least four hours.

The findings were presented Sunday at the American Thoracic Society's annual international conference in San Diego.

"GS-9411 administered by aerosol can effectively increase airway surface liquid and enhance mucous clearance in an animal model," study author Andrew Hirsh, senior director of drug discovery and preclinical development for Parion Sciences, a pharmaceutical company, said in a news release. "The results demonstrate that GS-9411 warrants further investigation as a new drug therapy to decrease respiratory infection and improve pulmonary function."

In cystic fibrosis, a genetic defect causes the airway to absorb sodium, and therefore moisture, too quickly. When the airway is too dry, the body can't clear mucus, a key defense mechanism of the respiratory system, Hirsh said. This deficiency can cause cystic fibrosis patients to have chronic respiratory infection and impaired lung function, he explained.

"The potency and the length of time that the drug was effective in cells and in animal studies was an outstanding feature that distinguishes this compound from other agents," he said.

More information

The March of Dimes has more about cystic fibrosis.



-- Kevin McKeever



SOURCE: American Thoracic Society, news release, May 17, 2009

Last Updated: May 18, 2009

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