ALLERGY, RESPIRATORY
Obesity May Raise Kids' Allergy Risk
Childhood Food Allergies on the Rise
Folic Acid Might Offer Allergy Relief
ALTERNATIVE MEDICINE
Health Tip: Anticipating Acupuncture
Grapefruit Compound Inhibits Hepatitis C Virus
U.S. Spends Billions On Alternative Medicine
ANIMAL CARE
'Comfort Dogs' Come to Emotional Rescue
Animals Respond to Acupuncture's Healing Touch
Separation Anxiety, Canine-Style
BONES & JOINTS
Bone Loss Stable on Restricted Calorie Diet
Yoga Can Ease Lower Back Pain
Heart Failure Raises Risk of Fractures
CANCER
Asthmatics Who Quit Smoking May Reverse Lung Damage
Ginger Can Ease Nausea From Chemotherapy Treatments
Supplements Might Reduce Breast Cancer Risk
CAREGIVING
Are Hospital Mobile Phones Dialing Up Superbugs?
Bariatric Surgery Centers Don't Deliver Better Outcomes
Weekend Admission May Be Riskier for GI Bleeding
CIRCULATORY SYSTEM
Years of Exposure to Traffic Pollution Raises Blood Pressure
Health Tip: Are You Anemic?
Tai Chi and Qigong Offer Many Health Benefits: Review
COSMETIC
New Genetic Links to Baldness Discovered
What to Do If You Have Unsightly Veins
Health Tip: After Liposuction
DENTAL, ORAL
Toothbrushing May Stave Off Heart Woes
Gum Disease May Reactivate AIDS Virus
Mom's Vitamin D Levels Affect Baby's Dental Health
DIABETES
Findings Challenge Tight Glucose Control for Critically Ill Patients
Boosting Vitamin D Can Do a Heart Good
Fructose-Sweetened Drinks Up Metabolic Syndrome Risk
DIET, NUTRITION
Folic Acid Might Offer Allergy Relief
School Meals Need to Get Healthier
Weight Loss Might Not Curb Knee Arthritis
DISABILITIES
Could Your Cell Phone Help Shield You From Alzheimer's?
Review Finds Marijuana May Help MS Patients
ENVIRONMENTAL HEALTH
Exposure to 9/11 Fumes Tied to Chronic Headaches
Topical Drugs May Pollute Waterways
Fertilizer Ban Makes a Difference
EYE CARE, VISION
High Temps Degrade Contact Lens Solution: Study
Americans Losing Sight of Eye Health
Just Like Skin, Eyes Can 'Burn' in Strong Sun
FITNESS
As Temperature Plummets, It's Still Safe to Exercise
Simple Steps Get Walkers Moving
Mom and Baby Alike May Benefit From Exercise
GASTROINTESTINAL PROBLEMS
Bowel Prep Harder on Women Than Men
Olive Oil May Protect Against Bowel Disease
Peppermint Oil, Fiber Can Fight Irritable Bowel
GENERAL HEALTH
More Single Women Are Having Babies
Why Am I So Tired? Could It Be Low Thyroid?
Heal Your Life® Tips for Living Well
HEAD & NECK
Zen May Thicken Brain, Thwart Pain
Ski Helmets Encouraged for All
Many Children Will Outgrow Headaches
HEALTH & TECHNOLOGY
Combating Myths About Seasonal Allergies
Save Your Aging Brain, Try Surfing The Web
Study Suggests Link Between Cell Phones and Brain Tumors
HEARING
Summer Sounds Can Lead to Hearing Loss
Noise Hurts Men's Hearing More, Study Shows
HEART & CARDIOVASCULAR
Ingredient in Dark Chocolate Could Guard Against Stroke
Lack of Vitamin D Linked to High Blood Pressure
Fatty Fish May Cut Heart Failure Risk in Men
INFECTIOUS DISEASE
Poor Restroom Cleaning Causes Cruise-Ship Sickness
The HPV Vaccine: Preventative Medicine or Human Sacrifice?
Viral Infection Might Trigger High Blood Pressure
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
Teen Stress May Have Roots in First Three Years of Life
Stomach Germ May Protect Against Asthma
Heart Defects in Newborns Linked to Antidepressants
MEN'S HEALTH
Eating Fast Until Full Triples Overweight Risk
Low Vitamin D Levels May Boost Men's Heart Attack Risk
Low Iron Levels Cut Cancer Risk in Men With PAD
MENTAL HEALTH
Daily dose of beet juice promotes brain health in older adults
Musicians' Brains Tuned to Emotions in Sound
Memory Loss Help from Brain Supplement Prevagen
PAIN
Acupuncture, Real or Fake, Eases Back Pain
Are We Exercising Pain Away? Not So Much.
'Cell Phone Elbow' -- A New Ill for the Wired Age
PHYSICAL THERAPY
PREGNANCY
Acupuncture May Ease Depression During Pregnancy
Breast-Feeding May Protect a Woman's Heart
Music of Mozart Soothes the Preemie Baby
SENIORS
Money May Matter, Health-Wise, in Old Age
Friends, Not Grandkids, Key to Happy Retirement
Exercise Helps Reduce Falls in Young and Old
SEXUAL HEALTH
SLEEP DISORDERS
Exercising Throat Muscles May Relieve Sleep Apnea
Lose Weight, Sleep Apnea May Improve
Better Sleep, Grades Seem to Go Up
WOMEN'S HEALTH
Omega-3 May Reduce Endometriosis Risk
Exercise, Weight Control May Keep Fibromyalgia at Bay
Air Pollution Slows Women's Marathon Times
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No Verdict Yet on Grape Seed Extract vs. Breast Cancer

THURSDAY, April 23 (HealthDay News) -- More research is needed to determine whether grape seed extract lowers hormone levels in postmenopausal women and provides protection against breast cancer, say researchers at the City of Hope cancer center in Duarte, Calif.

Because studies have suggested that grape seed extract inhibits aromatase, an enzyme that helps in estrogen production, the researchers looked at whether grape seed extract supplements could lower hormone levels in postmenopausal women.

What they found was a dramatic and sustained decrease in one patient with high baseline estrogen levels. But variable baseline hormone levels in the participants prevented them from reaching firm conclusions, they said.

Their findings were presented at the annual meeting of the American Association for Cancer Research, in Denver.

"We found that there are many variables that affect a woman's hormone level, including diet, concurrent medications and other supplements," the study's leader, Dr. Melanie Palomares, an assistant professor of cancer screening and prevention, said in a City of Hope news release.

"It was difficult to ascribe changes observed so far directly to the grape seed extract supplements, though three of the seven participants treated on the highest dose level had results showing promise," she said. "Our pharmacokinetic observations in this trial merit further investigations to evaluate the prevention benefits of grape seed extract."

Palomares is continuing the research with higher doses of grape seed extract in more carefully selected women. Once the most appropriate dose is determined, she plans to conduct a follow-up clinical trial to measure how grape seed extract affects breast tissue risk biomarkers.

More information

The U.S. National Cancer Institute has more about breast cancer prevention.



-- Robert Preidt



SOURCE: City of Hope, news release, April 21, 2009

Last Updated: April 23, 2009

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No Verdict Yet on Grape Seed Extract vs. Breast Cancer
Scott Bauer, U.S. Agricultural Research Service