ALLERGY, RESPIRATORY
Herbal Remedy Could Halt Peanut Allergy
Childhood Food Allergies on the Rise
Air Pollution May Raise Blood Pressure
ALTERNATIVE MEDICINE
No Verdict Yet on Grape Seed Extract vs. Breast Cancer
Cranberries May Help Prevent Urinary Tract Infections
Green Tea May Help Brain Cope With Sleep Disorders
ANIMAL CARE
'Comfort Dogs' Come to Emotional Rescue
Beware of Dog Bites
Rest Easy. When It Comes to Swine Flu, Your Pet Is Safe
BONES & JOINTS
Using a Balloon to Repair a Broken Back
Breast-feeding Might Shield Women From Rheumatoid Arthritis
Healthy adults have potential autoimmune disease-causing cells
CANCER
Vitamin D May Improve Melanoma Survival
Papaya Could Be a Cancer Fighter
Selenium, Omega-3s May Stave Off Colorectal Cancer
CAREGIVING
Early Exercise Boosts Outcomes for ICU Patients
Moms Who Breast-Feed Less Likely to Neglect Child
Birthmark or Blood Vessel Problem?
CIRCULATORY SYSTEM
Tai Chi and Qigong Offer Many Health Benefits: Review
Night Shift Work Hard on the Heart
Obesity Linked to Heart Failure Risk
COSMETIC
Contact Lenses Boost Kids' Self-Image
Study Evaluates Laser Therapies for Hair Removal
Health Tip: After Liposuction
DENTAL, ORAL
Gum Disease Treatment Doesn't Cut Preterm Birth Risk
Gum Care Helps Control Type 2 Diabetes and Its Complications
A Sweet Way to Shield Baby's Teeth
DIABETES
Patients' Photos Help Boost Radiologists' Accuracy
Insulin Resistance Tied to Peripheral Artery Disease
Diabetes Linked to Cognitive Problems
DIET, NUTRITION
Red Meat No No No But Oily Fish Yes Yes Yes
Want to Stop Cancer? You Can, Experts Say
Licorice May Block Absorption of Organ Transplant Drug
DISABILITIES
Could Your Cell Phone Help Shield You From Alzheimer's?
Review Finds Marijuana May Help MS Patients
ENVIRONMENTAL HEALTH
Global Warming Linked to Heightened Kidney Stone Risk
Hairspray Exposure Ups Risk for Birth Defect in Sons
Green Areas Lower Health Inequities Between Rich, Poor
EYE CARE, VISION
Eye Care Checkups Tied to Insurance Status
Vision Test for Young Children Called Unreliable
Guard Kids' Eyes Against Long-Term Sun Damage
FITNESS
Moderate Aerobic Exercise Lowers Diabetics' Liver Fat
School Phys. Ed. Injuries Up 150 Percent
Any Exercise Good After a Heart Attack
GASTROINTESTINAL PROBLEMS
Intestinal Bacteria Trigger Immune Response
New Guidelines Issued for Management of IBS
HRT Use Raises Risk of Stomach Trouble
GENERAL HEALTH
A Little Alcohol May Stave Off Alzheimer's
Good Sleepers More Likely to Eat Right
U.S. Spends Billions On Alternative Medicine
HEAD & NECK
Many Children Will Outgrow Headaches
Zen May Thicken Brain, Thwart Pain
Ski Helmets Encouraged for All
HEALTH & TECHNOLOGY
'Comfort Dogs' Come to Emotional Rescue
Subway Defibrillators Save Lives
Save Your Aging Brain, Try Surfing The Web
HEARING
Summer Sounds Can Lead to Hearing Loss
Noise Hurts Men's Hearing More, Study Shows
HEART & CARDIOVASCULAR
Laughter Can Boost Heart Health
Cherry-Enriched Diet Cut Heart Risks in Rats
Kids With Vitamin D Deficiency Linked to Heart Trouble
INFECTIOUS DISEASE
Swine Flu Closes Three Schools in NYC
The HPV Vaccine: Preventative Medicine or Human Sacrifice?
Dry Weather Boosts Odds of Flu Outbreaks
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
Traffic, Dust Linked to Asthma in Kids
When It Comes to Toys, Shop Smart, Shop Safe
Winter's Bitter Cold Poses Health Dangers
MEN'S HEALTH
Whole Grains, Bran May Fight Hypertension in Men
Soy Linked to Low Sperm Count
Countdown to Hair Loss
MENTAL HEALTH
Vitamin C Protects Some Elderly Men From Bone Loss
A Little Alcohol May Stave Off Alzheimer's
The 3LS Wellness Program for Reversing Chronic Symptoms and Creating Lasting Health
PAIN
'Cell Phone Elbow' -- A New Ill for the Wired Age
Are We Exercising Pain Away? Not So Much.
Acupuncture, Real or Fake, Eases Back Pain
PHYSICAL THERAPY
PREGNANCY
Acupuncture May Ease Depression During Pregnancy
Yoga's Benefits Outweigh Risks for Pregnant Women
Pregnant Women Exposed To Certain Pollutants Could Lower Childs IQ
SENIORS
Money May Matter, Health-Wise, in Old Age
Daily dose of beet juice promotes brain health in older adults
A Little Alcohol May Stave Off Alzheimer's
SEXUAL HEALTH
SLEEP DISORDERS
Better Sleep, Grades Seem to Go Up
Sleeping Could Help Women Lose The Baby Fat
6 to 8 Hours of Shut-Eye Is Optimal for Health
WOMEN'S HEALTH
Prenatal Stress May Boost Baby's Asthma Risk
Soy May Not Lead to Denser Breasts
Green Tea May Help Treat Uterine Fibroids
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No Verdict Yet on Grape Seed Extract vs. Breast Cancer

THURSDAY, April 23 (HealthDay News) -- More research is needed to determine whether grape seed extract lowers hormone levels in postmenopausal women and provides protection against breast cancer, say researchers at the City of Hope cancer center in Duarte, Calif.

Because studies have suggested that grape seed extract inhibits aromatase, an enzyme that helps in estrogen production, the researchers looked at whether grape seed extract supplements could lower hormone levels in postmenopausal women.

What they found was a dramatic and sustained decrease in one patient with high baseline estrogen levels. But variable baseline hormone levels in the participants prevented them from reaching firm conclusions, they said.

Their findings were presented at the annual meeting of the American Association for Cancer Research, in Denver.

"We found that there are many variables that affect a woman's hormone level, including diet, concurrent medications and other supplements," the study's leader, Dr. Melanie Palomares, an assistant professor of cancer screening and prevention, said in a City of Hope news release.

"It was difficult to ascribe changes observed so far directly to the grape seed extract supplements, though three of the seven participants treated on the highest dose level had results showing promise," she said. "Our pharmacokinetic observations in this trial merit further investigations to evaluate the prevention benefits of grape seed extract."

Palomares is continuing the research with higher doses of grape seed extract in more carefully selected women. Once the most appropriate dose is determined, she plans to conduct a follow-up clinical trial to measure how grape seed extract affects breast tissue risk biomarkers.

More information

The U.S. National Cancer Institute has more about breast cancer prevention.



-- Robert Preidt



SOURCE: City of Hope, news release, April 21, 2009

Last Updated: April 23, 2009

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No Verdict Yet on Grape Seed Extract vs. Breast Cancer
Scott Bauer, U.S. Agricultural Research Service