ALLERGY, RESPIRATORY
Air Pollution May Raise Blood Pressure
Combating Myths About Seasonal Allergies
Keep Asthma, Allergies at Bay for the Holidays
ALTERNATIVE MEDICINE
Tai Chi: An Ideal Exercise for Many People with Diabetes
Acupuncture May Trigger Natural Painkiller
Taking the Mystery Out of Hypnotherapy
ANIMAL CARE
Beware of Dog Bites
Safe Toys for Dogs
Rest Easy. When It Comes to Swine Flu, Your Pet Is Safe
BONES & JOINTS
Genes May Help Drive Rotator Cuff Injury
Healthy adults have potential autoimmune disease-causing cells
Vitamin C Protects Some Elderly Men From Bone Loss
CANCER
Family History Key Player in Brain Cancer Risk
Omega-3 May Safely Treat Precancerous Bowel Polyps
Well Water Might Raise Bladder Cancer Risk
CAREGIVING
Caring for Aging Loved Ones Can Be a Catch-22
Rapid Infant Weight Gain Linked to Childhood Obesity
Timing May Matter in Organ Donation Decisions
CIRCULATORY SYSTEM
Bad Marriages Harder on Women's Health
Anemia Rates Down for U.S. Women and Children
Laughter Can Boost Heart Health
COSMETIC
Study Evaluates Laser Therapies for Hair Removal
With Psoriasis, the Internet May Offer Hope
Mouse Study Finds Molecule That Tells Hair to Grow
DENTAL, ORAL
Hormones May Be to Blame for Women's Cavity Rates
Acid Drinks Blamed for Increase in Tooth Erosion
Dental Implants Need More Work Than Root Canals
DIABETES
Poor Blood Sugar Control After Heart Surgery Impacts Outcomes
Findings Challenge Tight Glucose Control for Critically Ill Patients
Insulin Resistance Tied to Peripheral Artery Disease
DIET, NUTRITION
Memory Loss Help from Brain Supplement Prevagen
Want to Stop Cancer? You Can, Experts Say
Low Vitamin D Levels May Initiate Cancer Development
DISABILITIES
Review Finds Marijuana May Help MS Patients
Could Your Cell Phone Help Shield You From Alzheimer's?
ENVIRONMENTAL HEALTH
Clear Skies Have Become Less So Over Time, Data Show
Agent Orange Exposure Tied to Prostate Cancer Return
Main Ingredients in Household Dust Come From Outdoors
EYE CARE, VISION
Brain Adapts to Age-Related Eye Disease
Eye Test Could Spot Diabetes Vision Trouble Early
Music Can Help Restore Stroke Patients' Sight
FITNESS
Be Healthy, Spend Less
Resistance Training Boosts Mobility in Knee Arthritis Patients
Fliers Can Keep Blood Clots at Bay
GASTROINTESTINAL PROBLEMS
Traditional Nonsurgical GERD Treatments Not Impressive
New Guidelines Issued for Management of IBS
Intestinal Bacteria Trigger Immune Response
GENERAL HEALTH
More Calcium And Dairy Products in Childhood Could Mean Longer Life
Eating Well And Keeping Active As You Grow Old Will Help You Stay Sharp
Simple Exercise Precautions To Help Keep Baby Boomers Fit
HEAD & NECK
Many Children Will Outgrow Headaches
Ski Helmets Encouraged for All
Zen May Thicken Brain, Thwart Pain
HEALTH & TECHNOLOGY
Using Light Therapy to Silence Harmful Brain Activity
The Internet Is Becoming One-Stop Shopping for Health Help
Study Suggests Link Between Cell Phones and Brain Tumors
HEARING
Summer Sounds Can Lead to Hearing Loss
Noise Hurts Men's Hearing More, Study Shows
HEART & CARDIOVASCULAR
Western Diet Linked To Heart Disease, Metabolic Syndrome
Ingredient in Dark Chocolate Could Guard Against Stroke
Research Shows Genetic Activity of Antioxidants
INFECTIOUS DISEASE
Dry Weather Boosts Odds of Flu Outbreaks
Surgical Masks Could Prevent Flu, Maybe
Chinese 'Devil Dung' Plant Could Be a Swine Flu Fighter
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
Pregnant Women Exposed To Certain Pollutants Could Lower Childs IQ
Keep Safety in Mind While Your Kids Are Cooling Off in the Water
Traffic Seems to Make Kids' Asthma Worse
MEN'S HEALTH
Low Iron Levels Cut Cancer Risk in Men With PAD
Physical Activity May Prolong Survival After Colon Cancer
Low Vitamin D Levels May Boost Men's Heart Attack Risk
MENTAL HEALTH
Cinnamon Breaks Up Brain Plaques, May Hold Key to Fighting Alzheimer’s
Mind Exercise Might Help Stroke Patients
Vitamin C Protects Some Elderly Men From Bone Loss
PAIN
'Cell Phone Elbow' -- A New Ill for the Wired Age
Are We Exercising Pain Away? Not So Much.
Tai Chi May Help Ease Fibromyalgia
PHYSICAL THERAPY
PREGNANCY
Exercise Boosts Bone Density in Breast-Feeding Moms
Exercise As Well As Acupuncture, May Ease Polycystic Ovarian Syndrome
Yoga's Benefits Outweigh Risks for Pregnant Women
SENIORS
High-Impact Activity May Be Good for Old Bones
Living Alone Increases Odds of Developing Dementia
Nighttime Urination Linked to Higher Death Rate Among Elderly
SEXUAL HEALTH
SLEEP DISORDERS
Pay Attention to Signs That Say You're Too Fatigued to Drive
Better Sleep, Grades Seem to Go Up
Lose Weight, Sleep Apnea May Improve
WOMEN'S HEALTH
Most Women With Osteoporosis Unaware of Raised Fracture Risk
Varicose Veins May Mask Larger Problem
Acupuncture May Help Relieve Polycystic Ovary Syndrome
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No Verdict Yet on Grape Seed Extract vs. Breast Cancer

THURSDAY, April 23 (HealthDay News) -- More research is needed to determine whether grape seed extract lowers hormone levels in postmenopausal women and provides protection against breast cancer, say researchers at the City of Hope cancer center in Duarte, Calif.

Because studies have suggested that grape seed extract inhibits aromatase, an enzyme that helps in estrogen production, the researchers looked at whether grape seed extract supplements could lower hormone levels in postmenopausal women.

What they found was a dramatic and sustained decrease in one patient with high baseline estrogen levels. But variable baseline hormone levels in the participants prevented them from reaching firm conclusions, they said.

Their findings were presented at the annual meeting of the American Association for Cancer Research, in Denver.

"We found that there are many variables that affect a woman's hormone level, including diet, concurrent medications and other supplements," the study's leader, Dr. Melanie Palomares, an assistant professor of cancer screening and prevention, said in a City of Hope news release.

"It was difficult to ascribe changes observed so far directly to the grape seed extract supplements, though three of the seven participants treated on the highest dose level had results showing promise," she said. "Our pharmacokinetic observations in this trial merit further investigations to evaluate the prevention benefits of grape seed extract."

Palomares is continuing the research with higher doses of grape seed extract in more carefully selected women. Once the most appropriate dose is determined, she plans to conduct a follow-up clinical trial to measure how grape seed extract affects breast tissue risk biomarkers.

More information

The U.S. National Cancer Institute has more about breast cancer prevention.



-- Robert Preidt



SOURCE: City of Hope, news release, April 21, 2009

Last Updated: April 23, 2009

Copyright © 2009 ScoutNews, LLC. All rights reserved.

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No Verdict Yet on Grape Seed Extract vs. Breast Cancer
Scott Bauer, U.S. Agricultural Research Service