ALLERGY, RESPIRATORY
Keep Asthma, Allergies at Bay for the Holidays
Using Music and Sports to Improve Kids' Asthma
Asthmatics Who Quit Smoking May Reverse Lung Damage
ALTERNATIVE MEDICINE
Acupuncture Eases Side Effects of Head, Neck Cancer Treatments
Grapefruit Compound Inhibits Hepatitis C Virus
Health Tip: Anticipating Acupuncture
ANIMAL CARE
Animals Respond to Acupuncture's Healing Touch
'Comfort Dogs' Come to Emotional Rescue
Rest Easy. When It Comes to Swine Flu, Your Pet Is Safe
BONES & JOINTS
New Clues to How Fish Oils Help Arthritis Patients
Childhood Dairy Intake Boosts Bone Health Later On
Sea Worm Inspires Novel Bone Glue
CANCER
Multiple Screening Strategy Boosts Cervical Cancer Detection
Lifting Weights Can Ease Arm Swelling in Breast Cancer Survivors
Yoga May Bring Calm to Breast Cancer Treatment
CAREGIVING
Study Casts Doubt on Influential Hospital Safety Survey
Baby's Sleep Position May Not Affect Severity of Head Flattening
Reduce Suffering, Urge Heart Failure Patients and Caregivers
CIRCULATORY SYSTEM
High Blood Fat Levels Common in Americans
Drink a Little Wine, Live a Little Longer
Obesity Linked to Heart Failure Risk
COSMETIC
Mouse Study Finds Molecule That Tells Hair to Grow
Science May Banish Bad Hair Days
Health Tip: After Liposuction
DENTAL, ORAL
An Oral Approach to Heart Disease
Biological Product Shows Promise Against Gum Disease
Hormones May Be to Blame for Women's Cavity Rates
DIABETES
24 Million Americans Had Diabetes in 2007
Drug May Not Help Diabetes-Related Eye Damage
Fish Twice a Week Cuts Diabetics' Kidney Risks
DIET, NUTRITION
More Calcium And Dairy Products in Childhood Could Mean Longer Life
Soluble Fiber, But Not Bran, Soothes Irritable Bowel
Decline of Underweight Children in U.S. Continue to Fall
DISABILITIES
Could Your Cell Phone Help Shield You From Alzheimer's?
Review Finds Marijuana May Help MS Patients
ENVIRONMENTAL HEALTH
Seasons Arriving 2 Days Earlier, Study Says
Dementia Underestimated in Developing Countries
Hypertension May Hit Black Males Earlier
EYE CARE, VISION
Nearly 18 Million Will Have Macular Degeneration by 2050
Half of U.S. Adults Lack 20/20 Vision
Retinal Gene Is Linked to Childhood Blindness
FITNESS
Study Shows Exercise Shields Against Osteoporosis
Exercise As Well As Acupuncture, May Ease Polycystic Ovarian Syndrome
Good Warm-Ups Could Halve Sports Injuries
GASTROINTESTINAL PROBLEMS
Bowel Prep Harder on Women Than Men
Japanese Herbals May Ease Gastro Woes
Intestinal Bacteria Trigger Immune Response
GENERAL HEALTH
Keep Safety in Mind While Your Kids Are Cooling Off in the Water
Adults Need To Get Thier Food Facts Straight
Poor Restroom Cleaning Causes Cruise-Ship Sickness
HEAD & NECK
Many Children Will Outgrow Headaches
Zen May Thicken Brain, Thwart Pain
Ski Helmets Encouraged for All
HEALTH & TECHNOLOGY
Save Your Aging Brain, Try Surfing The Web
Using Light Therapy to Silence Harmful Brain Activity
'Cell Phone Elbow' -- A New Ill for the Wired Age
HEARING
Noise Hurts Men's Hearing More, Study Shows
Summer Sounds Can Lead to Hearing Loss
HEART & CARDIOVASCULAR
Psychiatric Drugs Might Raise Cardiac Death Risk
Cherry-Enriched Diet Cut Heart Risks in Rats
Vitamin B3 May Help Repair Brain After a Stroke
INFECTIOUS DISEASE
Hand Washing 10 Times a Day May Help Keep Flu Away
The HPV Vaccine: Preventative Medicine or Human Sacrifice?
Swine Flu Now Reported in All 50 States
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
Wood Fires Can Harm the Youngest Lungs
Heart Defects in Newborns Linked to Antidepressants
Don't Leave Your Kids In The Car !
MEN'S HEALTH
Sunlight May Help Protect Men From Kidney Cancer
The Dark Side of Vegetarianism
Eating Fast Until Full Triples Overweight Risk
MENTAL HEALTH
Shop 'Til You Drop: You May Feel Better
Heal Your LifeŽ Tips for Living Well
Most Depressed Teens Don't Get Treatment
PAIN
Acupuncture, Real or Fake, Eases Back Pain
Are We Exercising Pain Away? Not So Much.
Alleviating Rheumatoid Arthritis
PHYSICAL THERAPY
PREGNANCY
Exercise Boosts Bone Density in Breast-Feeding Moms
Placebo Acupuncture Tied to Higher IVF Pregnancies
Exercise As Well As Acupuncture, May Ease Polycystic Ovarian Syndrome
SENIORS
Protein Deposits May Show Up Before Memory Problems Occur, Study Says
Nighttime Urination Linked to Higher Death Rate Among Elderly
Community Exercise Programs Boost Seniors' Strength
SEXUAL HEALTH
SLEEP DISORDERS
Sleeping Could Help Women Lose The Baby Fat
6 to 8 Hours of Shut-Eye Is Optimal for Health
Meditation May Help Put Primary Insomnia to Bed
WOMEN'S HEALTH
Pre-Pregnancy Weight Linked to Babies' Heart Problems
Acupuncture May Relieve Acid Indigestation In Pregnancy
Vitamin D Good for Breast Cancer Patients
Add your Article

Red-Grape Compound May Improve Diabetes

(HealthDay News) -- New research provides further insight into how a health-boosting compound found in red grapes may help the body fend off type 2 diabetes.

But scientists have only seen the effect in mice who received injections in the brain, and no evidence has emerged that consuming red wine or other products made with grapes will alleviate the blood sugar disease.

The findings do tell scientists about how the compound known as resveratrol works on the brain, said senior study author Roberto Coppari.

If scientists know that the brain is a "major player," then drug companies working on related research "will focus on a drug that will penetrate the brain," said Coppari, an assistant professor of internal medicine at University of Texas Southwestern Medical Center in Dallas.

Scientists have been excited about resveratrol, which is found in red grapes, red wine, pomegranates and some other foods, appears to extend the life spans of mice, even those fed a high-fat diet. Resveratrol appears to mimic the effects of severely restricting food intake, which helps a wide variety of animals live longer, Coppari said.

"You can take the spider, fish, and almost every animal in the planet, and give 70 percent of what the animal would normally eat, and you'll see beneficial effects," he said. "Of course, calorie restriction is very difficult to impose on people. You will feel hungry all the time."

In the new study, Coppari and colleagues looked at the effects of resveratrol on diabetes, not life span. Previous research has suggested that the compound helps the body fight off diabetes.

The researchers injected either resveratrol or a placebo into the brains of diet-induced and diabetic mice and watched to see what happened.

Over five weeks, insulin levels returned to half of normal levels in the mice that got the resveratrol injections, even though they were on high-fat diets. Researchers suspect resveratrol activated proteins in the brain called sirtuins.

The insulin levels in the other mice went up, apparently because of their diets.

So why not drink red wine to get the same effects? It won't work, Coppari said, since the amount of resveratrol in red wine is too low. Then there's the matter of the barrier between the bloodstream and the brain, which keeps things out of the brain.

"Clearly, administration of drugs to patients directly into the brain for chronic diseases is not feasible or realistic," said Lindsay Brown, of the University of Queensland's department of physiology and pharmacology in Australia.

"But this study may lead to the development of compounds that are more effective in crossing from the blood to the brain than is resveratrol," said Brown.

The study, which was supported by the American Heart Association, National Institutes of Health and American Diabetes Association, was published online in advance of its print publication in the December issue of the journal Endocrinology.

SOURCES: Roberto Coppari, Ph.D., assistant professor, internal medicine, University of Texas Southwestern Medical Center, Dallas; Lindsay Brown, Ph.D., University of Queensland's department of physiology and pharmacology, Australia; December 2009 Endocrinology