ALLERGY, RESPIRATORY
Molecule in Skin May Link Eczema and Asthma
Childhood Food Allergies on the Rise
'Safe' Ozone Levels May Not Be for Some
ALTERNATIVE MEDICINE
Garlic Yields Up Its Health Secret
Acupuncture, Real or Fake, Eases Back Pain
Naprapathy: A Hands-On Approach to Pain Management
ANIMAL CARE
Safe Toys for Dogs
Rest Easy. When It Comes to Swine Flu, Your Pet Is Safe
Separation Anxiety, Canine-Style
BONES & JOINTS
Tequila Plant May Help Fight Bone Loss
Yoga Can Ease Lower Back Pain
'Snowbirds' Beware the Climate Changes
CANCER
Strenuous Daily Workout May Keep Cancer at Bay
Vitamin D May Improve Melanoma Survival
More Americans Urged to Get Cancer Screenings
CAREGIVING
Obese Children More Likely to Suffer Lower Body Injuries
ER Less Likely to Diagnose Stroke in Younger Folks
Preventing Shaken Baby Syndrome
CIRCULATORY SYSTEM
Bye, Bye Back Fat?
Drink a Little Wine, Live a Little Longer
Tai Chi and Qigong Offer Many Health Benefits: Review
COSMETIC
With Psoriasis, the Internet May Offer Hope
Get Sugared!.... Its a sweet choice for hair removal
New Genetic Links to Baldness Discovered
DENTAL, ORAL
Rheumatoid Arthritis May Harm Gums
Hormones May Be to Blame for Women's Cavity Rates
Dental Implants Need More Work Than Root Canals
DIABETES
Drug May Not Help Diabetes-Related Eye Damage
Exercise Protects Black Women From Type 2 Diabetes
Laughter May Lower Heart Attack Risk in Diabetics
DIET, NUTRITION
Coffee Drinkers Might Live Longer
Lose Weight, Sleep Apnea May Improve
Eating More Soy May Be Good For Your Lung Function
DISABILITIES
Review Finds Marijuana May Help MS Patients
Could Your Cell Phone Help Shield You From Alzheimer's?
ENVIRONMENTAL HEALTH
Household Chemicals May Affect Cholesterol Levels
Hairspray Exposure Ups Risk for Birth Defect in Sons
1976 Italian Dioxin Release Damaged Babies' Thyroids
EYE CARE, VISION
Brain Adapts to Age-Related Eye Disease
Clues Found to Brain Mechanism Behind Migraines
It's a Whole New Outlook for Cataract Patients
FITNESS
Simple Exercise Precautions To Help Keep Baby Boomers Fit
Antioxidants Blunt Exercise Benefit, Study Shows
Diet, Exercise May Slow Kidney Disease Progression
GASTROINTESTINAL PROBLEMS
Gum Chewing May Speed Colon Surgery Recovery
Japanese Herbals May Ease Gastro Woes
Soothing Imagery May Help Rid Some Kids of Stomach Pain
GENERAL HEALTH
Keep Safety in Mind While Your Kids Are Cooling Off in the Water
Zen May Thicken Brain, Thwart Pain
Have Fun This Summer, But DO Be Careful
HEAD & NECK
Zen May Thicken Brain, Thwart Pain
Many Children Will Outgrow Headaches
Ski Helmets Encouraged for All
HEALTH & TECHNOLOGY
E-Mailing Your Way to Healthier Habits
Magnet Therapy May Ease Hard-to-Treat Depression
Study Suggests Link Between Cell Phones and Brain Tumors
HEARING
Summer Sounds Can Lead to Hearing Loss
Noise Hurts Men's Hearing More, Study Shows
HEART & CARDIOVASCULAR
Kids With Vitamin D Deficiency Linked to Heart Trouble
Fructose Boosts Blood Pressure, Studies Find
Rheumatoid Arthritis a Threat to the Heart
INFECTIOUS DISEASE
Hand Washing 10 Times a Day May Help Keep Flu Away
Swine Flu Loves a Crowd
Chinese 'Devil Dung' Plant Could Be a Swine Flu Fighter
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
Wood Fires Can Harm the Youngest Lungs
Scary Toxins Make Halloween Face Paints Questionable
Babies Who Eat Fish Lower Eczema Risk
MEN'S HEALTH
The Dark Side of Vegetarianism
Physical Activity May Prolong Survival After Colon Cancer
Noise Hurts Men's Hearing More, Study Shows
MENTAL HEALTH
Eight Spiritual Universal Principles in the Art of Practice
A Little Alcohol May Stave Off Alzheimer's
A Simple 'Thank You' Brings Rewards to All
PAIN
Tai Chi May Help Ease Fibromyalgia
Are We Exercising Pain Away? Not So Much.
Acupuncture, Real or Fake, Eases Back Pain
PHYSICAL THERAPY
PREGNANCY
Music of Mozart Soothes the Preemie Baby
Placebo Acupuncture Tied to Higher IVF Pregnancies
Before Conceiving, Take Folic Acid for One Full Year
SENIORS
Older Adults May Have Some Immunity to Swine Flu
Want Better Health in the New Year, Add Exercise to Your Day
A Little Alcohol May Stave Off Alzheimer's
SEXUAL HEALTH
SLEEP DISORDERS
Moderate Aerobics May Ease Insomnia Symptoms
Sleeping Could Help Women Lose The Baby Fat
Pay Attention to Signs That Say You're Too Fatigued to Drive
WOMEN'S HEALTH
Caffeine in Pregnancy Associated With Low Birth Weight Risk
Supportive Weigh-In Program Keeps Pounds Off
Natural Childbirth Moms More Attuned to Babies' Cry
Add your Article

Red-Grape Compound May Improve Diabetes

(HealthDay News) -- New research provides further insight into how a health-boosting compound found in red grapes may help the body fend off type 2 diabetes.

But scientists have only seen the effect in mice who received injections in the brain, and no evidence has emerged that consuming red wine or other products made with grapes will alleviate the blood sugar disease.

The findings do tell scientists about how the compound known as resveratrol works on the brain, said senior study author Roberto Coppari.

If scientists know that the brain is a "major player," then drug companies working on related research "will focus on a drug that will penetrate the brain," said Coppari, an assistant professor of internal medicine at University of Texas Southwestern Medical Center in Dallas.

Scientists have been excited about resveratrol, which is found in red grapes, red wine, pomegranates and some other foods, appears to extend the life spans of mice, even those fed a high-fat diet. Resveratrol appears to mimic the effects of severely restricting food intake, which helps a wide variety of animals live longer, Coppari said.

"You can take the spider, fish, and almost every animal in the planet, and give 70 percent of what the animal would normally eat, and you'll see beneficial effects," he said. "Of course, calorie restriction is very difficult to impose on people. You will feel hungry all the time."

In the new study, Coppari and colleagues looked at the effects of resveratrol on diabetes, not life span. Previous research has suggested that the compound helps the body fight off diabetes.

The researchers injected either resveratrol or a placebo into the brains of diet-induced and diabetic mice and watched to see what happened.

Over five weeks, insulin levels returned to half of normal levels in the mice that got the resveratrol injections, even though they were on high-fat diets. Researchers suspect resveratrol activated proteins in the brain called sirtuins.

The insulin levels in the other mice went up, apparently because of their diets.

So why not drink red wine to get the same effects? It won't work, Coppari said, since the amount of resveratrol in red wine is too low. Then there's the matter of the barrier between the bloodstream and the brain, which keeps things out of the brain.

"Clearly, administration of drugs to patients directly into the brain for chronic diseases is not feasible or realistic," said Lindsay Brown, of the University of Queensland's department of physiology and pharmacology in Australia.

"But this study may lead to the development of compounds that are more effective in crossing from the blood to the brain than is resveratrol," said Brown.

The study, which was supported by the American Heart Association, National Institutes of Health and American Diabetes Association, was published online in advance of its print publication in the December issue of the journal Endocrinology.

SOURCES: Roberto Coppari, Ph.D., assistant professor, internal medicine, University of Texas Southwestern Medical Center, Dallas; Lindsay Brown, Ph.D., University of Queensland's department of physiology and pharmacology, Australia; December 2009 Endocrinology