ALLERGY, RESPIRATORY
Folic Acid Might Offer Allergy Relief
Using Music and Sports to Improve Kids' Asthma
Air Pollution May Raise Blood Pressure
ALTERNATIVE MEDICINE
Acupuncture May Ease Depression During Pregnancy
Needling Away Your Headaches With Acupuncture
Licorice May Block Absorption of Organ Transplant Drug
ANIMAL CARE
Separation Anxiety, Canine-Style
Rest Easy. When It Comes to Swine Flu, Your Pet Is Safe
Animals Respond to Acupuncture's Healing Touch
BONES & JOINTS
Weight Loss Might Not Curb Knee Arthritis
Childhood Dairy Intake Boosts Bone Health Later On
Rheumatoid Arthritis Hits Women Harder
CANCER
Sharing Cancer Info May Be Empowering
Spice Compounds May Stem Tumor Growth
Mineral May Reduce High-Risk Bladder Disease
CAREGIVING
Medication Errors Could Be Cut: Experts
Birthmark or Blood Vessel Problem?
Bariatric Surgery Centers Don't Deliver Better Outcomes
CIRCULATORY SYSTEM
Anemia Rates Down for U.S. Women and Children
Night Shift Work Hard on the Heart
Smog Tougher on the Obese
COSMETIC
Gum Chewing May Cut Craving for Snacks
Study Evaluates Laser Therapies for Hair Removal
New Genetic Links to Baldness Discovered
DENTAL, ORAL
Amino Acid May Be Key to Strong Teeth
Gum Care Helps Control Type 2 Diabetes and Its Complications
A Sweet Way to Shield Baby's Teeth
DIABETES
Vitamin K Slows Insulin Resistance in Older Men
Findings Challenge Tight Glucose Control for Critically Ill Patients
Whole Grains Take a Bite Out of Type 2 Diabetes Risk
DIET, NUTRITION
Atkins Diet Tougher on Heart After Weight Loss
More Calcium And Dairy Products in Childhood Could Mean Longer Life
6 Million U.S. Kids Lack Enough Vitamin D
DISABILITIES
Could Your Cell Phone Help Shield You From Alzheimer's?
Review Finds Marijuana May Help MS Patients
ENVIRONMENTAL HEALTH
Vest Monitors 'Individual' Air Pollution
Gene Mutation May Cause Some Cases of Seasonal Affective Disorder
Seasons Arriving 2 Days Earlier, Study Says
EYE CARE, VISION
Unconscious Learning: In the Eye of the Beholder?
Impotence Drugs Don't Harm Vision: Study
Sports Eye Injuries Leading Cause of Blindness in Youths
FITNESS
Occupational Therapy Plus Exercise Benefits Osteoarthritis
Exercise As Well As Acupuncture, May Ease Polycystic Ovarian Syndrome
Exercise Extends Life of Kidney Patients
GASTROINTESTINAL PROBLEMS
Bowel Prep Harder on Women Than Men
Peppermint Oil, Fiber Can Fight Irritable Bowel
Intestinal Bacteria Trigger Immune Response
GENERAL HEALTH
A Little Alcohol May Stave Off Alzheimer's
Swine Flu May Pose Problems for Pregnant Women
Should the FDA Regulate Tobacco?
HEAD & NECK
Ski Helmets Encouraged for All
Many Children Will Outgrow Headaches
Zen May Thicken Brain, Thwart Pain
HEALTH & TECHNOLOGY
Study Suggests Link Between Cell Phones and Brain Tumors
Using Light Therapy to Silence Harmful Brain Activity
'Comfort Dogs' Come to Emotional Rescue
HEARING
Noise Hurts Men's Hearing More, Study Shows
Summer Sounds Can Lead to Hearing Loss
HEART & CARDIOVASCULAR
Coffee Is Generally Heart-Friendly
Boosting Vitamin D Can Do a Heart Good
Psychiatric Drugs Might Raise Cardiac Death Risk
INFECTIOUS DISEASE
Swine Flu Now Reported in All 50 States
Swine Flu Closes Three Schools in NYC
Poor Restroom Cleaning Causes Cruise-Ship Sickness
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
Teen Stress May Have Roots in First Three Years of Life
Too Many Infants Short on Vitamin D
School Meals Need to Get Healthier
MEN'S HEALTH
Could Chinese Herb Be a Natural Viagra?
Low Vitamin D Levels May Boost Men's Heart Attack Risk
Strenuous Daily Workout May Keep Cancer at Bay
MENTAL HEALTH
Love Hormone May Ease Discussion of Painful Topics
Memory Loss Help from Brain Supplement Prevagen
Chocolate a Sweet Pick-Me-Up for the Depressed
PAIN
Are We Exercising Pain Away? Not So Much.
Acupuncture, Real or Fake, Eases Back Pain
Alleviating Rheumatoid Arthritis
PHYSICAL THERAPY
PREGNANCY
Pregnant Women Exposed To Certain Pollutants Could Lower Childs IQ
Music of Mozart Soothes the Preemie Baby
For Baby and Mom Alike, Breast-Feeding May Be Best
SENIORS
Tai Chi and Qigong Offer Many Health Benefits: Review
As You Age, Better Health Means Better Sex
More Whole Grains May Mean Less Fat
SEXUAL HEALTH
SLEEP DISORDERS
Moderate Aerobics May Ease Insomnia Symptoms
Sleeping Could Help Women Lose The Baby Fat
Pay Attention to Signs That Say You're Too Fatigued to Drive
WOMEN'S HEALTH
Whole Grains, Bran May Fight Hypertension in Men
Calcium Helps Ward Off Colon Cancer
For Women, Moderate Midlife Drinking Linked to Healthier Old Age
Add your Article

Saliva Test Could Monitor Type 2 Diabetes

By Steven Reinberg
HealthDay Reporter

TUESDAY, Jan. 20 (HealthDay News) -- Scientists say they are on the verge of developing a saliva test for monitoring type 2 diabetes, which might someday replace invasive blood tests.

For the first time, researchers from Oregon and India have identified proteins in saliva that appear more frequently in people with diabetes than in non-diabetics. Using these proteins, they are working to develop a test to monitor and perhaps diagnose the condition.

However, Dr. Umesh Masharani, an associate clinical professor of medicine at the University of California, San Francisco, doesn't think this approach is going to replace current blood tests any time soon.

"I think this is an interesting and novel approach," Masharani said. "I do not think this approach will be used in the diagnosis or treatment of diabetes any time in the near future. It is interesting, I think, for research studies in diabetes."

The report was published in the Jan. 2 issue of the Journal of Proteome Research.

For the study, Paturi V. Rao, from the departments of Endocrinology and Metabolism and Medicine at Nizam's Institute of Medical Sciences University in Hyderabad, India, and colleagues analyzed saliva samples from people with and without type 2 diabetes. Their goal was to find proteins associated with the blood sugar disease.

The researchers found 65 proteins that occurred twice as frequently in the people with diabetes than in those without the condition.

Using these proteins, Rao's team hopes to develop a noninvasive test for diabetes screening, detection and monitoring.

Rao's group thinks the pain involved with current diabetes monitoring causes many diabetics to be lax in monitoring their condition. A noninvasive test could make it easier and less painful for patients to keep track of their blood sugar levels.

"As recent studies have shown that early and multi-factorial intervention in diabetes prevents cardiovascular complications and mortality, advances in understanding molecular aspects of preclinical diabetes will further facilitate accurate diagnosis and early intervention," the authors wrote.

Diabetes expert Dr. Charles F. Burant, a professor of internal medicine at the University of Michigan, isn't convinced that a test using proteins in saliva is needed.

"I think it has minimal clinical impact," Burant said. "To be a valid biomarker, a test has to be sensitive and specific. We don't know the value of either for any of the proteins at the present time."

The biggest question is why this is needed, Burant noted. "Diabetes and prediabetes have a valid biomarker -- glucose -- that is the measure of the disease state. Thus, this is interesting biochemistry and raises questions why these changes occur, but the clinical utility is unclear."

More information

For more about type 2 diabetes, visit the American Diabetes Association.



SOURCES: Umesh Masharani, M.D., associate clinical professor, medicine, University of California, San Francisco; Charles F. Burant, M.D., Ph.D., professor, internal medicine, University of Michigan, Ann Arbor; Jan. 2, 2009, Journal of Proteome Research

Last Updated: Jan. 20, 2009

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