ALLERGY, RESPIRATORY
New Spray Could Benefit Cystic Fibrosis Patients
Childhood Food Allergies on the Rise
Keep Asthma, Allergies at Bay for the Holidays
ALTERNATIVE MEDICINE
Acupuncture May Not Help Hot Flashes
New Insights Show Ginseng Fights Inflammation
Tai Chi: An Ideal Exercise for Many People with Diabetes
ANIMAL CARE
Animals Respond to Acupuncture's Healing Touch
Rest Easy. When It Comes to Swine Flu, Your Pet Is Safe
Beware of Dog Bites
BONES & JOINTS
Tai Chi May Help Ward Off Knee Pain in Seniors
Almost Half of Adults Will Develop Knee Osteoarthritis by 85
Too Few Screened for Abdominal Aneurysm, Study Says
CANCER
Massage Therapy Helps Those With Advanced Cancer
Ginger Can Ease Nausea From Chemotherapy Treatments
Some Spices Cut Cancer Risk That Comes With Grilled Burgers
CAREGIVING
Birthmark or Blood Vessel Problem?
Early Exercise Boosts Outcomes for ICU Patients
Study Casts Doubt on Influential Hospital Safety Survey
CIRCULATORY SYSTEM
Health Tip: Are You Anemic?
Walk 100 Steps a Minute for 'Moderate' Exercise
Years of Exposure to Traffic Pollution Raises Blood Pressure
COSMETIC
Contact Lenses Boost Kids' Self-Image
Gum Chewing May Cut Craving for Snacks
Science May Banish Bad Hair Days
DENTAL, ORAL
Gum Care Helps Control Type 2 Diabetes and Its Complications
Scientists Find Gene for Tooth Enamel
Amino Acid May Be Key to Strong Teeth
DIABETES
Fish Twice a Week Cuts Diabetics' Kidney Risks
Chamomile Tea May Ward Off Diabetes Damage
Formula Puts Doctor, Patient Glucose Readings on Same Page
DIET, NUTRITION
Olive Oil May Be Key to Mediterranean Diet's Benefits
Soluble Fiber, But Not Bran, Soothes Irritable Bowel
Oregano Shown to be the Most Powerful Culinary Herb
DISABILITIES
Review Finds Marijuana May Help MS Patients
Could Your Cell Phone Help Shield You From Alzheimer's?
ENVIRONMENTAL HEALTH
Most Mt. Everest Deaths Occur Near Summit During Descent
Gas Stove Emissions Boost Asthma in Inner-City Kids
What's Cookin'? It Could Be Air Pollution
EYE CARE, VISION
Florida Vision Test Law: Fewer Traffic Deaths Among Elderly
Nutrient-Rich Diet Lowers Risk of Age-Related Eye Disease
Eye Test Could Spot Diabetes Vision Trouble Early
FITNESS
Exercise 30 Minutes a Day? Who Knew!
Exercise As Well As Acupuncture, May Ease Polycystic Ovarian Syndrome
Almost Two-Thirds of Americans Meet Exercise Guidelines
GASTROINTESTINAL PROBLEMS
Peppermint Oil, Fiber Can Fight Irritable Bowel
Traditional Nonsurgical GERD Treatments Not Impressive
Intestinal Bacteria Trigger Immune Response
GENERAL HEALTH
Brisk Walk Can Help Leave Common Cold Behind
Healthy Living Adds Years to Life
Man Dies of Brain Inflammation Caused by Deer Tick Virus
HEAD & NECK
Many Children Will Outgrow Headaches
Ski Helmets Encouraged for All
Zen May Thicken Brain, Thwart Pain
HEALTH & TECHNOLOGY
Study Suggests Link Between Cell Phones and Brain Tumors
'Comfort Dogs' Come to Emotional Rescue
Magnet Therapy May Ease Hard-to-Treat Depression
HEARING
Summer Sounds Can Lead to Hearing Loss
Noise Hurts Men's Hearing More, Study Shows
HEART & CARDIOVASCULAR
Fish Oil Supplements Help With Heart Failure
Man's Best Friend Helps Mend Broken Hearts
Research Shows Genetic Activity of Antioxidants
INFECTIOUS DISEASE
Surgical Masks Could Prevent Flu, Maybe
Swine Flu Loves a Crowd
More Medicinal Uses for Pomegranate
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
3 Home Habits Help Youngsters Stay Slim
Plastics Chemical Tied to Aggression in Young Girls
Folic Acid Reduces Infant Heart Defects
MEN'S HEALTH
Vigorous Exercise Cuts Stroke Risk for Men, Not Women
Low Vitamin D Levels May Boost Men's Heart Attack Risk
Low Iron Levels Cut Cancer Risk in Men With PAD
MENTAL HEALTH
Musicians' Brains Tuned to Emotions in Sound
Vitamin C Protects Some Elderly Men From Bone Loss
Have a Goal in Life? You Might Live Longer
PAIN
Are We Exercising Pain Away? Not So Much.
Tai Chi May Help Ease Fibromyalgia
Acupuncture, Real or Fake, Eases Back Pain
PHYSICAL THERAPY
PREGNANCY
Pre-Pregnancy Weight Linked to Babies' Heart Problems
Breast-Feeding May Protect a Woman's Heart
Breast-Feeding Benefits Moms and Babies
SENIORS
Community Exercise Programs Boost Seniors' Strength
Seniors Who Volunteer May Live Longer
Martial Arts Training May Save Seniors' Hips
SEXUAL HEALTH
SLEEP DISORDERS
Pay Attention to Signs That Say You're Too Fatigued to Drive
Sleeping Could Help Women Lose The Baby Fat
Lose Weight, Sleep Apnea May Improve
WOMEN'S HEALTH
Sleeping Could Help Women Lose The Baby Fat
Supplements Might Reduce Breast Cancer Risk
Pre-Pregnancy Weight Linked to Babies' Heart Problems
Add your Article

Saliva Test Could Monitor Type 2 Diabetes

By Steven Reinberg
HealthDay Reporter

TUESDAY, Jan. 20 (HealthDay News) -- Scientists say they are on the verge of developing a saliva test for monitoring type 2 diabetes, which might someday replace invasive blood tests.

For the first time, researchers from Oregon and India have identified proteins in saliva that appear more frequently in people with diabetes than in non-diabetics. Using these proteins, they are working to develop a test to monitor and perhaps diagnose the condition.

However, Dr. Umesh Masharani, an associate clinical professor of medicine at the University of California, San Francisco, doesn't think this approach is going to replace current blood tests any time soon.

"I think this is an interesting and novel approach," Masharani said. "I do not think this approach will be used in the diagnosis or treatment of diabetes any time in the near future. It is interesting, I think, for research studies in diabetes."

The report was published in the Jan. 2 issue of the Journal of Proteome Research.

For the study, Paturi V. Rao, from the departments of Endocrinology and Metabolism and Medicine at Nizam's Institute of Medical Sciences University in Hyderabad, India, and colleagues analyzed saliva samples from people with and without type 2 diabetes. Their goal was to find proteins associated with the blood sugar disease.

The researchers found 65 proteins that occurred twice as frequently in the people with diabetes than in those without the condition.

Using these proteins, Rao's team hopes to develop a noninvasive test for diabetes screening, detection and monitoring.

Rao's group thinks the pain involved with current diabetes monitoring causes many diabetics to be lax in monitoring their condition. A noninvasive test could make it easier and less painful for patients to keep track of their blood sugar levels.

"As recent studies have shown that early and multi-factorial intervention in diabetes prevents cardiovascular complications and mortality, advances in understanding molecular aspects of preclinical diabetes will further facilitate accurate diagnosis and early intervention," the authors wrote.

Diabetes expert Dr. Charles F. Burant, a professor of internal medicine at the University of Michigan, isn't convinced that a test using proteins in saliva is needed.

"I think it has minimal clinical impact," Burant said. "To be a valid biomarker, a test has to be sensitive and specific. We don't know the value of either for any of the proteins at the present time."

The biggest question is why this is needed, Burant noted. "Diabetes and prediabetes have a valid biomarker -- glucose -- that is the measure of the disease state. Thus, this is interesting biochemistry and raises questions why these changes occur, but the clinical utility is unclear."

More information

For more about type 2 diabetes, visit the American Diabetes Association.



SOURCES: Umesh Masharani, M.D., associate clinical professor, medicine, University of California, San Francisco; Charles F. Burant, M.D., Ph.D., professor, internal medicine, University of Michigan, Ann Arbor; Jan. 2, 2009, Journal of Proteome Research

Last Updated: Jan. 20, 2009

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