ALLERGY, RESPIRATORY
Molecule in Skin May Link Eczema and Asthma
Overweight Moms More Likely to Have Asthmatic Kids
Climate Change Could Sting Allergy, Asthma Sufferers
ALTERNATIVE MEDICINE
Soybean Chemicals May Reduce Effects of Menopause
Acupuncture May Trigger Natural Painkiller
Licorice May Block Absorption of Organ Transplant Drug
ANIMAL CARE
Beware of Dog Bites
Animals Respond to Acupuncture's Healing Touch
Safe Toys for Dogs
BONES & JOINTS
Many Americans Fall Short on Their Vitamin D
Sea Worm Inspires Novel Bone Glue
Rheumatoid Arthritis Hits Women Harder
CANCER
Smoking Exposure Now Linked to Colon, Breast Cancers
Green Tea Compound Slowed Chronic Lymphocytic Leukemia
Method for Treating Cervical Lesions May Pose Pregnancy Risks
CAREGIVING
What Moms Learned May Be Passed to Offspring
Are Hospital Mobile Phones Dialing Up Superbugs?
Caregivers Face Multiple Strains Tending Older Parents
CIRCULATORY SYSTEM
Smog Tougher on the Obese
An Apple a Day May Help Keep Heart Disease Away
Health Tip: Are You Anemic?
COSMETIC
Contact Lenses Boost Kids' Self-Image
With Psoriasis, the Internet May Offer Hope
The Acne Drug Accutane More Than Doubles Depression Risk
DENTAL, ORAL
Sports Drinks May Be Tough on Teeth
Gummy Bears Join Cavity Fight
Obesity Boosts Gum Disease Risk
DIABETES
Abnormal Heart Rhythm Boosts Death Risk for Diabetics
Spices, Herbs Boost Health for Diabetics
Strict Blood Sugar Lowering Won't Ease Diabetes Heart Risk
DIET, NUTRITION
Common Antioxidant Might Slow Parkinson's
Red Meat No No No But Oily Fish Yes Yes Yes
The Raw Food Diet
DISABILITIES
Could Your Cell Phone Help Shield You From Alzheimer's?
Review Finds Marijuana May Help MS Patients
ENVIRONMENTAL HEALTH
Rainy Areas in U.S. Show Higher Autism Rates
Golf Course Insecticides Pose Little Danger to Players
Exposure to 9/11 Fumes Tied to Chronic Headaches
EYE CARE, VISION
Brain Pressure More Likely to Cause Vision Loss in Men
Impotence Drugs Don't Harm Vision: Study
Nearly 18 Million Will Have Macular Degeneration by 2050
FITNESS
FDA Mandates New Warnings for Botox
Football Can Shrink Players
Go To Work But Skip The Car
GASTROINTESTINAL PROBLEMS
Soothing Imagery May Help Rid Some Kids of Stomach Pain
Japanese Herbals May Ease Gastro Woes
Traditional Nonsurgical GERD Treatments Not Impressive
GENERAL HEALTH
Dry Weather Boosts Odds of Flu Outbreaks
Biomarkers May Help Measure Rate of Decline in Dementia
Diet, Exercise May Slow Kidney Disease Progression
HEAD & NECK
Many Children Will Outgrow Headaches
Ski Helmets Encouraged for All
Zen May Thicken Brain, Thwart Pain
HEALTH & TECHNOLOGY
Study Suggests Link Between Cell Phones and Brain Tumors
Combating Myths About Seasonal Allergies
The Internet Is Becoming One-Stop Shopping for Health Help
HEARING
Summer Sounds Can Lead to Hearing Loss
Noise Hurts Men's Hearing More, Study Shows
HEART & CARDIOVASCULAR
Cocoa in Chocolate May Be Good for the Heart
Toothbrushing May Stave Off Heart Woes
Vigorous Exercise Cuts Stroke Risk for Men, Not Women
INFECTIOUS DISEASE
Grapefruit Compound Inhibits Hepatitis C Virus
Chinese 'Devil Dung' Plant Could Be a Swine Flu Fighter
Swine Flu Closes Three Schools in NYC
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
Music May Temper Pain in Preemies
Protect Your Kids From Swine Flu While at Camp
Better Sleep, Grades Seem to Go Up
MEN'S HEALTH
Exercise May Prevent Prostate Cancer: Study Shows
Soy Linked to Low Sperm Count
Vigorous Exercise Cuts Stroke Risk for Men, Not Women
MENTAL HEALTH
A Simple 'Thank You' Brings Rewards to All
Eight Spiritual Universal Principles in the Art of Practice
Most Depressed Teens Don't Get Treatment
PAIN
Are We Exercising Pain Away? Not So Much.
'Cell Phone Elbow' -- A New Ill for the Wired Age
Acupuncture, Real or Fake, Eases Back Pain
PHYSICAL THERAPY
PREGNANCY
Alternative Treatments May Boost IVF Success
Placebo Acupuncture Tied to Higher IVF Pregnancies
Sleeping Could Help Women Lose The Baby Fat
SENIORS
More Whole Grains May Mean Less Fat
As You Age, Better Health Means Better Sex
High-Impact Activity May Be Good for Old Bones
SEXUAL HEALTH
SLEEP DISORDERS
Better Sleep, Grades Seem to Go Up
Lose Weight, Sleep Apnea May Improve
Moderate Aerobics May Ease Insomnia Symptoms
WOMEN'S HEALTH
Natural Oils Help Lower Body Fat For Some
Women Smokers Lose 14.5 Years Off Life Span
Calcium Helps Ward Off Colon Cancer
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Scientists ID New Genes Tied to Crohn's Disease

MONDAY, June 30 (HealthDay News) -- Researchers have identified 21 new genetic regions implicated in Crohn's disease, bringing to 32 the total number of genes and loci -- regions of the genome typically including one or more genes that are known to increase susceptibility to the disease.

For this study, published in the journal Nature Genetics, the international team of scientists and clinicians analyzed DNA samples from almost 12,000 people in Europe and North America.

"We now know of more than 30 genetic regions that affect susceptibility to Crohn's disease. These explain only about a fifth of the genetic risk, which implies that there may be hundreds of genes implicated in the disease, each increasing susceptibility by a small amount," lead author Dr. Jeffery Barrett, of the Wellcome Trust Centre for Human Genetics at the University of Oxford, said in a prepared statement.

"Whilst this study shows the power of genome-wide association studies to reveal the genetics behind common diseases, it also highlights the complexity of diseases such as Crohn's," Barrett noted.

Crohn's disease causes inflammation of the gastrointestinal tract, resulting in pain, ulcers and diarrhea. Onset of the disease typically occurs between the ages of 15 and 40, but it can strike at any age. As many as 80 percent of people with Crohn's disease will require surgery.

Along with identifying potential new targets for the development of drugs to treat Crohn's, this study found that loci with genes associated with Crohn's are also implicated in a number of other diseases such as asthma, diabetes, rheumatoid arthritis and psoriasis.

"It's too early for us to say how Crohn's disease and many of these other diseases, including asthma, are linked at a biological level," study co-author Dr. Miles Parkes, consultant gastroenterologist at Addenbrooke's Hospital and the University of Cambridge, said in a prepared statement. "However, we are building up a picture of the biology underlying Crohn's disease, and the more we understand about the underlying biology of these diseases, the better equipped we will be to treat them."

"Genetics, and particularly the large scale approach of genome-wide association studies, offers much hope for understanding the biological causes of complex diseases," Dr. Mark Walport, director of the Wellcome Trust, said in a prepared statement. "Studies such as this also highlight the important relationships between different diseases, and, as such, may offer valuable insights into the pathways that lead to common symptoms such as inflammation."

The Wellcome Trust is a charity that funds biomedical research.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about Crohn's disease.



-- Robert Preidt



SOURCE: Wellcome Trust, news release, June 29, 2008

Last Updated: June 30, 2008

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