ALLERGY, RESPIRATORY
Childhood Food Allergies on the Rise
Using Music and Sports to Improve Kids' Asthma
Asthmatics Who Quit Smoking May Reverse Lung Damage
ALTERNATIVE MEDICINE
Placebo Acupuncture Tied to Higher IVF Pregnancies
Tai Chi: An Ideal Exercise for Many People with Diabetes
Grapefruit Compound Inhibits Hepatitis C Virus
ANIMAL CARE
'Comfort Dogs' Come to Emotional Rescue
Safe Toys for Dogs
Rest Easy. When It Comes to Swine Flu, Your Pet Is Safe
BONES & JOINTS
Childhood Dairy Intake Boosts Bone Health Later On
Varicose, Spider Veins May Be Inevitable for Some
More Faces Being Spared in Motor Vehicle Accidents
CANCER
Vitamin E, Selenium and Soy Won't Prevent Prostate Cancer
Researchers ID Genetic Markers for Esophageal Cancer
Seaweed May Help Treat Lymphoma
CAREGIVING
Late-Life Fatherhood May Lower Child's Intelligence
Depression, PTSD Common Among Lung Transplant Patient Caregivers
Medication Errors Could Be Cut: Experts
CIRCULATORY SYSTEM
Migraines in Pregnancy Boost Vascular Risks
An Apple a Day May Help Keep Heart Disease Away
Anemia Rates Down for U.S. Women and Children
COSMETIC
Study Evaluates Laser Therapies for Hair Removal
Wrinkle Fillers Need Better Label Warnings: FDA Panel
Get Sugared!.... Its a sweet choice for hair removal
DENTAL, ORAL
Holistic Dentistry-My View
Mom's Vitamin D Levels Affect Baby's Dental Health
Laser Technology Spots Cavities Before They Start
DIABETES
Exercise Protects Black Women From Type 2 Diabetes
Diabetes Linked to Cognitive Problems
Vitamin K Slows Insulin Resistance in Older Men
DIET, NUTRITION
Trans-Fat Ban In New York City Is Proving successful
Eat Light - Live Longer
Even in 'Last Supper,' Portion Sizes Have Grown
DISABILITIES
Review Finds Marijuana May Help MS Patients
Could Your Cell Phone Help Shield You From Alzheimer's?
ENVIRONMENTAL HEALTH
EPA Alerts Seniors to Carbon Monoxide Dangers
Gene Mutation May Cause Some Cases of Seasonal Affective Disorder
Flame-Retardant Chemical Linked to Conception Problems
EYE CARE, VISION
Gene-Transfer Proves Safe for Vision Problem
Protein Might One Day Prevent Blindness
FDA Goes After Unapproved Eye Washes, Skin Ointments
FITNESS
Meditation May Help Put Primary Insomnia to Bed
Any Exercise Good After a Heart Attack
Strenuous Daily Workout May Keep Cancer at Bay
GASTROINTESTINAL PROBLEMS
Intestinal Bacteria Trigger Immune Response
Olive Oil May Protect Against Bowel Disease
New Yogurt May Ease Stomach Ulcers
GENERAL HEALTH
Eating More Soy May Be Good For Your Lung Function
Healthy Eating While On Vacation
Time to Remind Teens About Sun Protection
HEAD & NECK
Many Children Will Outgrow Headaches
Ski Helmets Encouraged for All
Zen May Thicken Brain, Thwart Pain
HEALTH & TECHNOLOGY
'Cell Phone Elbow' -- A New Ill for the Wired Age
E-Mailing Your Way to Healthier Habits
Combating Myths About Seasonal Allergies
HEARING
Noise Hurts Men's Hearing More, Study Shows
Summer Sounds Can Lead to Hearing Loss
HEART & CARDIOVASCULAR
Ginkgo Won't Prevent Heart Attack, Stroke in Elderly
Rheumatoid Arthritis a Threat to the Heart
Low Vitamin D Levels Linked to Heart Disease
INFECTIOUS DISEASE
The HPV Vaccine: Preventative Medicine or Human Sacrifice?
Poor Restroom Cleaning Causes Cruise-Ship Sickness
Swine Flu Now Reported in All 50 States
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
Gene Variation Found in Boys With Delinquent Peers
Traffic, Dust Linked to Asthma in Kids
Stomach Germ May Protect Against Asthma
MEN'S HEALTH
Exercise May Prevent Prostate Cancer: Study Shows
The Dark Side of Vegetarianism
Could Chinese Herb Be a Natural Viagra?
MENTAL HEALTH
Keeping Mentally Active Seems To Keep The Brain Active
Worries About Weight Are Tied to Teen Suicide Tries
Psychotherapy Can Boost Happiness More Than Money
PAIN
Are We Exercising Pain Away? Not So Much.
Tai Chi May Help Ease Fibromyalgia
'Cell Phone Elbow' -- A New Ill for the Wired Age
PHYSICAL THERAPY
PREGNANCY
Obesity May Affect Fertility in Young Womene
Placebo Acupuncture Tied to Higher IVF Pregnancies
Calcium Supplements Cut Blood Lead Levels During Pregnancy
SENIORS
Vitamin D May Help Keep Aging at Bay
Tai Chi May Help Ward Off Knee Pain in Seniors
Older Adults May Have Some Immunity to Swine Flu
SEXUAL HEALTH
SLEEP DISORDERS
Daylight Savings: Not a Bright Time for All
Lose Weight, Sleep Apnea May Improve
Sleeping Could Help Women Lose The Baby Fat
WOMEN'S HEALTH
Spice Compounds May Stem Tumor Growth
How Much Fish to Eat While Pregnant?
Postmenopausal Women With Breast Cancer Face Joint Issues
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Scientists ID New Genes Tied to Crohn's Disease

MONDAY, June 30 (HealthDay News) -- Researchers have identified 21 new genetic regions implicated in Crohn's disease, bringing to 32 the total number of genes and loci -- regions of the genome typically including one or more genes that are known to increase susceptibility to the disease.

For this study, published in the journal Nature Genetics, the international team of scientists and clinicians analyzed DNA samples from almost 12,000 people in Europe and North America.

"We now know of more than 30 genetic regions that affect susceptibility to Crohn's disease. These explain only about a fifth of the genetic risk, which implies that there may be hundreds of genes implicated in the disease, each increasing susceptibility by a small amount," lead author Dr. Jeffery Barrett, of the Wellcome Trust Centre for Human Genetics at the University of Oxford, said in a prepared statement.

"Whilst this study shows the power of genome-wide association studies to reveal the genetics behind common diseases, it also highlights the complexity of diseases such as Crohn's," Barrett noted.

Crohn's disease causes inflammation of the gastrointestinal tract, resulting in pain, ulcers and diarrhea. Onset of the disease typically occurs between the ages of 15 and 40, but it can strike at any age. As many as 80 percent of people with Crohn's disease will require surgery.

Along with identifying potential new targets for the development of drugs to treat Crohn's, this study found that loci with genes associated with Crohn's are also implicated in a number of other diseases such as asthma, diabetes, rheumatoid arthritis and psoriasis.

"It's too early for us to say how Crohn's disease and many of these other diseases, including asthma, are linked at a biological level," study co-author Dr. Miles Parkes, consultant gastroenterologist at Addenbrooke's Hospital and the University of Cambridge, said in a prepared statement. "However, we are building up a picture of the biology underlying Crohn's disease, and the more we understand about the underlying biology of these diseases, the better equipped we will be to treat them."

"Genetics, and particularly the large scale approach of genome-wide association studies, offers much hope for understanding the biological causes of complex diseases," Dr. Mark Walport, director of the Wellcome Trust, said in a prepared statement. "Studies such as this also highlight the important relationships between different diseases, and, as such, may offer valuable insights into the pathways that lead to common symptoms such as inflammation."

The Wellcome Trust is a charity that funds biomedical research.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about Crohn's disease.



-- Robert Preidt



SOURCE: Wellcome Trust, news release, June 29, 2008

Last Updated: June 30, 2008

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