ALLERGY, RESPIRATORY
Herbal Remedy Could Halt Peanut Allergy
'Safe' Ozone Levels May Not Be for Some
Combating Myths About Seasonal Allergies
ALTERNATIVE MEDICINE
Could Chinese Herb Be a Natural Viagra?
No Verdict Yet on Grape Seed Extract vs. Breast Cancer
Higher Vitamin D Intake Could Cut Cancer Risk
ANIMAL CARE
Beware of Dog Bites
Safe Toys for Dogs
Separation Anxiety, Canine-Style
BONES & JOINTS
More Faces Being Spared in Motor Vehicle Accidents
Gene Therapy May Ease Rheumatoid Arthritis
Postmenopausal Women With Breast Cancer Face Joint Issues
CANCER
Multiple Screening Strategy Boosts Cervical Cancer Detection
Hypnosis Cuts Hot Flashes for Breast Cancer Survivors
Many Cancer Survivors Don't Adopt Healthy Lifestyle
CAREGIVING
MRSA Infections Spreading to Kids in Community
Babies Born in High Pollen Months at Wheezing Risk
Omega-3 Fatty Acid May Help 'Preemie' Girls' Brains
CIRCULATORY SYSTEM
An Apple a Day May Help Keep Heart Disease Away
Bad Marriages Harder on Women's Health
Common Antioxidant Might Slow Parkinson's
COSMETIC
Contact Lenses Boost Kids' Self-Image
New Genetic Links to Baldness Discovered
Gum Chewing May Cut Craving for Snacks
DENTAL, ORAL
Holistic Dentistry-My View
Study Links Osteoporosis Drugs to Jaw Trouble
Health Tip: At Risk for Gingivitis
DIABETES
Arthritis Hits More Than Half of Diabetics
Spices, Herbs Boost Health for Diabetics
Boosting Vitamin D Can Do a Heart Good
DIET, NUTRITION
Antioxidants Abound in Cereals, Popcorn, Whole-Grain Snacks
Vitamin D Vital for the Heart
Fruit Even Healthier Than Thought: Study Shows
DISABILITIES
Could Your Cell Phone Help Shield You From Alzheimer's?
Review Finds Marijuana May Help MS Patients
ENVIRONMENTAL HEALTH
Fertilizer Ban Makes a Difference
Greenhouse Gases Hazardous to Your Health
EPA Alerts Seniors to Carbon Monoxide Dangers
EYE CARE, VISION
Brain Pressure More Likely to Cause Vision Loss in Men
Brain Adapts to Age-Related Eye Disease
Ordinary Chores Cause Half of All Eye Injuries
FITNESS
Bursts of Vigorous Activity Appear to Be a 'Stress-Buffer'
Higher Fitness Levels Tied to Lower Heart, Death Risks
Early Exercise Boosts Outcomes for ICU Patients
GASTROINTESTINAL PROBLEMS
New Guidelines Issued for Management of IBS
New Yogurt May Ease Stomach Ulcers
Soothing Imagery May Help Rid Some Kids of Stomach Pain
GENERAL HEALTH
Stressed and Exhausted: An Introduction to Adrenal Fatigue
Family Medicine Cabinet Top Source Of Kid's Poisonings
Eating Healthy : You Can Live Longer
HEAD & NECK
Many Children Will Outgrow Headaches
Zen May Thicken Brain, Thwart Pain
Ski Helmets Encouraged for All
HEALTH & TECHNOLOGY
'Cell Phone Elbow' -- A New Ill for the Wired Age
Using Light Therapy to Silence Harmful Brain Activity
'Comfort Dogs' Come to Emotional Rescue
HEARING
Noise Hurts Men's Hearing More, Study Shows
Summer Sounds Can Lead to Hearing Loss
HEART & CARDIOVASCULAR
Arteries Age Twice as Fast in Smokers
Most Fast-Food French Fries Cooked in Unhealthiest Oil
Obese People Seem to Do Better With Heart Disease
INFECTIOUS DISEASE
Older Adults May Have Some Immunity to Swine Flu
More Medicinal Uses for Pomegranate
Viral Infection Might Trigger High Blood Pressure
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
Traffic, Dust Linked to Asthma in Kids
Protect Your Kids From Swine Flu While at Camp
Quick Orthopedic Repair Can Save Young Shoulders
MEN'S HEALTH
Varicose Veins May Mask Larger Problem
Low Vitamin D Levels May Boost Men's Heart Attack Risk
Noise Hurts Men's Hearing More, Study Shows
MENTAL HEALTH
Using the Mind to Heal the Heart
Breast-Fed Baby May Mean Better Behaved Child
Worries About Weight Are Tied to Teen Suicide Tries
PAIN
Acupuncture, Real or Fake, Eases Back Pain
Are We Exercising Pain Away? Not So Much.
'Cell Phone Elbow' -- A New Ill for the Wired Age
PHYSICAL THERAPY
PREGNANCY
Alternative Treatments May Boost IVF Success
Mom's Extra Pregnancy Pounds May Raise Child's Heart Risks
Breast-Feeding May Protect a Woman's Heart
SENIORS
Money May Matter, Health-Wise, in Old Age
Living Alone Increases Odds of Developing Dementia
Many Cancer Survivors Don't Adopt Healthy Lifestyle
SEXUAL HEALTH
SLEEP DISORDERS
Pay Attention to Signs That Say You're Too Fatigued to Drive
Better Sleep, Grades Seem to Go Up
Meditation May Help Put Primary Insomnia to Bed
WOMEN'S HEALTH
Broccoli May Help Battle Breast Cancer
Air Pollution Slows Women's Marathon Times
Supplements Might Reduce Breast Cancer Risk
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Scientists ID New Genes Tied to Crohn's Disease

MONDAY, June 30 (HealthDay News) -- Researchers have identified 21 new genetic regions implicated in Crohn's disease, bringing to 32 the total number of genes and loci -- regions of the genome typically including one or more genes that are known to increase susceptibility to the disease.

For this study, published in the journal Nature Genetics, the international team of scientists and clinicians analyzed DNA samples from almost 12,000 people in Europe and North America.

"We now know of more than 30 genetic regions that affect susceptibility to Crohn's disease. These explain only about a fifth of the genetic risk, which implies that there may be hundreds of genes implicated in the disease, each increasing susceptibility by a small amount," lead author Dr. Jeffery Barrett, of the Wellcome Trust Centre for Human Genetics at the University of Oxford, said in a prepared statement.

"Whilst this study shows the power of genome-wide association studies to reveal the genetics behind common diseases, it also highlights the complexity of diseases such as Crohn's," Barrett noted.

Crohn's disease causes inflammation of the gastrointestinal tract, resulting in pain, ulcers and diarrhea. Onset of the disease typically occurs between the ages of 15 and 40, but it can strike at any age. As many as 80 percent of people with Crohn's disease will require surgery.

Along with identifying potential new targets for the development of drugs to treat Crohn's, this study found that loci with genes associated with Crohn's are also implicated in a number of other diseases such as asthma, diabetes, rheumatoid arthritis and psoriasis.

"It's too early for us to say how Crohn's disease and many of these other diseases, including asthma, are linked at a biological level," study co-author Dr. Miles Parkes, consultant gastroenterologist at Addenbrooke's Hospital and the University of Cambridge, said in a prepared statement. "However, we are building up a picture of the biology underlying Crohn's disease, and the more we understand about the underlying biology of these diseases, the better equipped we will be to treat them."

"Genetics, and particularly the large scale approach of genome-wide association studies, offers much hope for understanding the biological causes of complex diseases," Dr. Mark Walport, director of the Wellcome Trust, said in a prepared statement. "Studies such as this also highlight the important relationships between different diseases, and, as such, may offer valuable insights into the pathways that lead to common symptoms such as inflammation."

The Wellcome Trust is a charity that funds biomedical research.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about Crohn's disease.



-- Robert Preidt



SOURCE: Wellcome Trust, news release, June 29, 2008

Last Updated: June 30, 2008

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